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Taurine as a possible therapy for immunosenescence and inflammaging

Cellular & Molecular Immunology volume 21, pages 3–5 (2024)Cite this article

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In their recent Science article, Singh et al. identified taurine as an endogenously produced anti-inflammatory, anti-immunosenescence, and anti-aging molecule. The authors also show that restoring taurine to its “youthful” levels prevents inflammation, boosts the immune response, and delays inflammaging/aging.

Much scientific effort has been invested in therapeutic strategies to increase our lifespan and healthspan, and there is a general belief that inflammaging and, particularly, immunosenescence can be manipulated to delay or reverse aging-associated degeneration [1]. In this context, many exogenous and endogenous “anti-aging” molecules are being investigated to extend the number of years we spend in good health [1].

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Acknowledgements

Research in the author’s laboratory is supported by the Ministry of Science and Innovation and the Spanish Research Agency through FEDER funds (PID2021-1261520B-100) (MICINN/AEI/FEDER, EU). CBMSO receives an institutional grant from the Fundación Ramón Areces, Spain.

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  1. Centro de Biología Molecular Severo Ochoa (CBMSO). Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid (CSIC/UAM), C/Nicolás Cabrera 1, Campus de Cantoblanco, 28049, Madrid, Spain

    José M. Izquierdo

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Correspondence to José M. Izquierdo.

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Izquierdo, J.M. Taurine as a possible therapy for immunosenescence and inflammaging. Cell Mol Immunol 21, 3–5 (2024). https://doi.org/10.1038/s41423-023-01062-5

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  • DOI: https://doi.org/10.1038/s41423-023-01062-5

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