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Crystal structure of estrogen sulphotransferase

Nature Structural Biology volume 4, pages 904–908 (1997)Cite this article

The structure of estrogen sulphotransferase has been solved in the presence of inactive cofactor PAP and substrate 17β-estradiol. This structure reveals structural similarities between cytosolic sulphotransf erases and nucleotide kinases.

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References

  1. Strott, C.A. Endocrine Rev. 17, 670–697 (1996).

    Article  CAS  Google Scholar 

  2. Luu-The, V., Bernier, F. & Dufort, I. J. Endocrinol. 150, S87–S97 (1996).

    CAS  PubMed  Google Scholar 

  3. Weinshilboum, R.M. et al. FASEB J. 11, 3–14 (1997).

    Article  CAS  Google Scholar 

  4. Coughtrie, M.W.H. et al. Chem.-Biol. Interact. 92, 247–256 (1994).

    Article  CAS  Google Scholar 

  5. Surh, Y., Blomquist, J.C., Liem, A. & Miller, J.A. Carcinogenesis 11, 1451–1460 (1990).

    Article  CAS  Google Scholar 

  6. Falany, J.L. & Falany, C.N. Cancer Research 56, 1551–1555 (1996).

    CAS  PubMed  Google Scholar 

  7. Sharp, S., Anderson, J.M. & Coughtrie, M.W.H. Eur. J. Cancer 30A (11), 1654–1659 (1994).

    Article  CAS  Google Scholar 

  8. Song, W., Moore, R., McLachlan, J.A. & Negishi, M. Endocrinology 136, 2477–2484 (1995).

    Article  CAS  Google Scholar 

  9. Holm, L. & Sander, C. Structure 5, 165–171 (1997).

    Article  CAS  Google Scholar 

  10. Müller-Dieckmann, H. & Schulz, G.E. J. Mol. Biol. 236, 361–367 (1994).

    Article  Google Scholar 

  11. Muller, C.W. & Schulz, G.E. J. Mol. Biol. 202, 909–912 (1988).

    Article  CAS  Google Scholar 

  12. Stehle, T. & Schulz, G.E. J. Mol. Biol. 224, 1127–1141 (1992).

    Article  CAS  Google Scholar 

  13. Chiba, H., Komatsu, K., Lee, Y.C., Tomizuka, T. & Strott, C.A. Proc. Natl. Acad. Sci. USA 92, 8176–8179 (1995).

    Article  CAS  Google Scholar 

  14. Komatsu, K., Driscoll, W.J., Koh, Y.C. & Strott, C.A. Biochem. Biophys. Res. Commun. 204, 1178–1185 (1994).

    Article  CAS  Google Scholar 

  15. Driscoll, W.J., Komatsu, K. & Strott, C.A. Proc. Natl. Acad. Sci. USA 92, 12328–12332 (1995).

    Article  CAS  Google Scholar 

  16. Marsolais, F. & Varin, L. J. Biol. Chem. 270, 30458–30463 (1995)

    Article  CAS  Google Scholar 

  17. Bond, C.S. et al. Structure 5, 277–289 (1997).

    Article  CAS  Google Scholar 

  18. Sowadski, J.M., Handschumacher, M.D., Krishna Murthy, H.M., Foster, B.A. & Wyckoff, H.W. J. Mol. Biol. 186, 417–433 (1985).

    Article  CAS  Google Scholar 

  19. Homma, H. et al. Bioche. et Biophys. Acta 1296, 159–166 (1996).

    Google Scholar 

  20. Bridger, W.A., James, M.N.G., Fraser, M.E. & J. Biol. Chem. 269, 10883–10890 (1994).

    PubMed  Google Scholar 

  21. Otwinowski, Z. & Minor, W. Meth. Enz. 276, 307–326 (1996).

    Google Scholar 

  22. McRee, D.E. J. Mol. Graphics 10, 44–46 (1992).

    Article  Google Scholar 

  23. Furey, W. & Swaminathan, S Meth. Enz 277, 590–619 (1997).

    CAS  Google Scholar 

  24. Collaborative Computational Project No. 4. Acta Crystallogr. D50, 760–763 (1994).

  25. Jones, T.A., Zou, J.-Y., Cowan, S.W. & Kjelgaard, M. Acta Crystallogr. A47, 110–119 (1991).

    Article  CAS  Google Scholar 

  26. Brunger, A.T., Kuriyan, J. & Karplus, M. Science 235, 458–460 (1987).

    Article  CAS  Google Scholar 

  27. Jiang, J.S. & Brunger, A.T. J. Mol. Bio. 243, 100–115 (1994).

    Article  CAS  Google Scholar 

  28. Rice, L.M. & Brunger, A.T. Proteins: Structure, function, and Genetics 19, 277–290 (1994).

    Article  CAS  Google Scholar 

  29. Laskowski, R.A., MacArthur, M.W., Moss, D.S. & Thornton, J.M. J. Appl. Crystallogr. 26, 283–291 (1993).

    Article  CAS  Google Scholar 

  30. Evans, S.V. J. Mol. Graphics 11, 134–138 (1993).

    Article  CAS  Google Scholar 

  31. Zhu, X.Y., Veronese, M.E. Sansom, L.N. & McManus, M.E. Biochem. Biophys. Res. Commun. 192, 671–676 (1993).

    Article  CAS  Google Scholar 

  32. Otterness, D.M. et al. Mol. Pharmacol. 41, 865–872 (1992).

    CAS  PubMed  Google Scholar 

  33. Ananvoranich, S., Varin, L., Gulick, P. & Ibrahim, R. Plant Physiol. 106, 485–491 (1994).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Pharmacogenetics section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA

    Yoshimitsu Kakuta, Masahiko Negishi & Lars C. Pedersen

  2. Laboratory of Quantitative and Computational Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, 27709, USA

    Lee G. Pedersen

  3. Department of Biochemistry and Biophysics, The University of North Carolina, Chapel Hill, North Carolina, 27514, USA

    Charles W. Carter

Authors
  1. Yoshimitsu Kakuta
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  2. Lee G. Pedersen
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  3. Charles W. Carter
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  4. Masahiko Negishi
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  5. Lars C. Pedersen
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Kakuta, Y., Pedersen, L., Carter, C. et al. Crystal structure of estrogen sulphotransferase. Nat Struct Mol Biol 4, 904–908 (1997). https://doi.org/10.1038/nsb1197-904

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