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PCOS in 2015

New insights into the genetics of polycystic ovary syndrome

Nature Reviews Endocrinology volume 12, pages 74–75 (2016)Cite this article

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A Corrigendum to this article was published on 29 January 2016

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In 2015, large-scale genetic and functional studies brought us closer to understanding the underlying aetiology of polycystic ovary syndrome (PCOS), implicating genes involved in modulation of gonadotropin and neuroendocrine action, ovarian androgen biosynthesis and possibly insulin action, providing clues to the evolutionary path and potential evolutionary advantages of PCOS.

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Change history

  • 29 January 2016

    In the original published article, the second bullet point in the Key advances should have read: "Genetic variation in epidermal growth factor receptor genes affects susceptibility to PCOS5". This error has been corrected in the HTML and PDF versions of the article.

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  1. Medical College of Georgia, Georgia Regents University, 1120 15th Street, Augusta, 30912, Georgia, USA

    Ricardo Azziz

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  1. Ricardo Azziz
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Correspondence to Ricardo Azziz.

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R.A. has acted as a consultant for Global PET and KinDex Pharmaceuticals.

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Azziz, R. New insights into the genetics of polycystic ovary syndrome. Nat Rev Endocrinol 12, 74–75 (2016). https://doi.org/10.1038/nrendo.2015.230

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