Orbitofrontal cortex damage impairs decision making. A recent article in Nature shows that this brain region is critical for computing the subjective value of an outcome and using this value signal to make choices
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Wallis, J. Evaluating apples and oranges. Nat Neurosci 9, 596–598 (2006). https://doi.org/10.1038/nn0506-596
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DOI: https://doi.org/10.1038/nn0506-596