Intracellular traffic of the HIV-1 transactivator protein Tat appears essential for pathogenesis, and interdiction by immunization-induced antibodies to Tat should prevent AIDS.
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Goldstein, G. HIV–1 Tat protein as a potential AIDS vaccine. Nat Med 2, 960–964 (1996). https://doi.org/10.1038/nm0996-960
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DOI: https://doi.org/10.1038/nm0996-960
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