The cellular RNA helicase RIG-I initiates an antiviral response through the activation of several protein kinases. The physical link between RIG-I and these 'downstream' kinases has now been identified.
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Katie Ris
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Sen, G., Sarkar, S. Hitching RIG to action. Nat Immunol 6, 1074–1076 (2005). https://doi.org/10.1038/ni1105-1074
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DOI: https://doi.org/10.1038/ni1105-1074
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