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Spotlight on IL-22-producing NK cell receptor–expressing mucosal lymphocytes

New findings show that a subpopulation of mucosal RORγt+ cells expresses natural killer cell receptors and produces interleukin 22. These innate immune cells may be pivotal in maintaining mucosal homeostasis.

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Figure 1: In the gut, different subsets of RORγt+ cells exist.

Katie Vicari

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Malmberg, KJ., Ljunggren, HG. Spotlight on IL-22-producing NK cell receptor–expressing mucosal lymphocytes. Nat Immunol 10, 11–12 (2009). https://doi.org/10.1038/ni0109-11

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