Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letters to Editor
  • Published:

Differential Staining Patterns of Heterochromatin in Man

Abstract

QUINACRINE staining1 can be used to distinguish between different heterochromatic segments in various organisms and Giemsa staining has been used to locate constitutive heterochromatin in human chromosomes2. In using both these techniques on human chromosome preparations we have found certain specific staining properties of hetero-chromatic segments which suggest the existence of at least two different constitutive heterochromatins.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Vosa, C. G., Chromosoma, 30, 366 (1970).

    Article  Google Scholar 

  2. Arrighi, F., and Hsu, T. C., Cytogenetics (in the press).

  3. Zech, L., Exp. Cell Res., 58, 141 (1969).

    Article  Google Scholar 

  4. Pearson, P. L., Bobrow, M., and Vosa, C. G., Nature, 226, 78 (1970).

    Article  CAS  Google Scholar 

  5. Laberge, C., and Gagné, R., Johns Hopkins Med. J., 128, 79 (1971).

    CAS  PubMed  Google Scholar 

  6. Caspersson, T., Zech, L., Johansson, L., and Modest, E. J., Chromosoma, 30, 215 (1970).

    Article  CAS  Google Scholar 

  7. Sasaki, M. S., and Makino, S., Amer. J. Human Genet., 15, 24 (1963).

    CAS  Google Scholar 

  8. The London Conference on the Normal Human Karyotype, Cytogenetics, 2, 264 (1963).

  9. Ockey, C. H., Cytogenetics, 8, 272 (1969).

    Article  Google Scholar 

  10. Sumner, A. T., Robinson, J. A., and Evans, H. J., Nature New Biology, 229, 231 (1971).

    Article  CAS  Google Scholar 

  11. Pardue, M. L., and Gall, J. G., Science, 168, 1356 (1970).

    Article  CAS  Google Scholar 

  12. Jones, K. W., Nature, 225, 912 (1970).

    Article  CAS  Google Scholar 

  13. Corneo, G., Ginelli, E., and Polli, E., J. Mol. Biol., 48, 319 (1970).

    Article  CAS  Google Scholar 

  14. Lima-de-Faria, A., Handbook of Molecular Cytology (edit. by J Lima-de-Faria, A.) (North-Holland, Amsterdam, 1969).

    Google Scholar 

  15. Caspersson, T., Farber, S., Foley, G. E., Kudynowski, J., Modest, E. J., Simonsson, E., Wagh, V., and Zech, L., Exp. Cell Res., 49, 219 (1968).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GAGNÉ, R., TANGUAY, R. & LABERGE, C. Differential Staining Patterns of Heterochromatin in Man. Nature New Biology 232, 29–30 (1971). https://doi.org/10.1038/newbio232029a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/newbio232029a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing