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Site-selective reactions

Exploiting intramolecularity

Selective reaction of one alcohol among many in complex molecules can be achieved by the use of a catalyst that forms a single covalent bond to a nearby functional group.

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Figure 1: Catalytic approaches to site-selective functionalization of complex molecules.

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Correspondence to André M. Beauchemin.

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Beauchemin, A. Exploiting intramolecularity. Nature Chem 5, 731–732 (2013). https://doi.org/10.1038/nchem.1737

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