Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Putting induced pluripotent stem cells to the test

Human induced pluripotent stem cells are found to be nearly identical to embryonic stem cells, supporting their suitability for clinical applications.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Method to compare human pluripotent stem cells of different origin without the influence of genetic background.

References

  1. Takahashi, K. et al. Cell 131, 861–872 (2007).

    Article  CAS  Google Scholar 

  2. Choi, J. et al. Nat. Biotechnol. 33, 1173–1181 (2015).

    Article  CAS  Google Scholar 

  3. Soares, F.A., Sheldon, M., Rao, M., Mummery, C. & Vallier, L. Stem Cell Rep. 3, 931–939 (2014).

    Article  Google Scholar 

  4. Vallier, L. et al. Stem Cells 27, 2655–2666 (2009).

    Article  CAS  Google Scholar 

  5. Bock, C. et al. Cell 144, 439–452 (2011).

    Article  CAS  Google Scholar 

  6. Osafune, K. et al. Nat. Biotechnol. 26, 313–315 (2008).

    Article  CAS  Google Scholar 

  7. Kim, K. et al. Nature 467, 285–290 (2010).

    Article  CAS  Google Scholar 

  8. Rouhani, F. et al. PLoS Genet. 10, e1004432 (2014).

    Article  Google Scholar 

  9. Kajiwara, M. et al. Proc. Natl. Acad. Sci. USA 109, 12538–12543 (2012).

    Article  CAS  Google Scholar 

  10. Stadtfeld, M. et al. Nature 465, 175–181 (2010).

    Article  CAS  Google Scholar 

  11. ENCODE Project Consortium. Nature 489, 57–74 (2012).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ludovic Vallier.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vallier, L. Putting induced pluripotent stem cells to the test. Nat Biotechnol 33, 1145–1146 (2015). https://doi.org/10.1038/nbt.3401

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.3401

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research