Abstract
SUPEROVULATION through the administration of exogenous gonadotropins1 has been widely used in mice for experimental purposes, and cytogenetic evidence has shown2,4 that the technique does not affect adversely the chromosome constitution of either released ova or zygotes. We have noticed, however, that the incidence of triploidy increased considerably among zygotes obtained through superovulation followed by natural mating in adult A-strain mice5. We have therefore investigated the origin of the extra genome in such embryos.
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TAKAGI, N., SASAKI, M. Digynic triploidy after superovulation in mice. Nature 264, 278–281 (1976). https://doi.org/10.1038/264278a0
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DOI: https://doi.org/10.1038/264278a0
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