Abstract
THERE have been several attempts to activate mammalian eggs to parthenogenesis. Pincus et al.1–8 first showed that rabbit eggs can be activated in vitro or in situ with various physical and chemical agents and that some of these eggs can begin to develop. Four living young were born which were considered to have been of parthenogenetic origin3,4,7,8. Thibault9–11 and Chang12,13, working with eggs of the same species, confirmed earlier suggestions that cold shock is an effective parthenogenetic agent and that eggs so activated in vitro or in vivo can develop to blastocysts. But although some parthenogenetic blastocysts were morphologically normal and diploid13, development beyond implantation was never observed11,13.
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TARKOWSKI, A., WITKOWSKA, A. & NOWICKA, J. Experimental Parthenogenesis in the Mouse. Nature 226, 162–165 (1970). https://doi.org/10.1038/226162a0
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DOI: https://doi.org/10.1038/226162a0
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