Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

In vivo Detection of Circulating Gas Emboli associated with Decompression Sickness using the Doppler Flowmeter

Abstract

THE ultrasonic Doppler flowmeter1 has been used to measure blood flow in several animal species2,3 and man4,5 by monitoring the frequency shift produced in the scattering of ultrasonic waves by moving blood cells. The extreme sensitivity of this instrument to air bubbles in the circulating fluid is a familiar nuisance encountered during in vitro testing and calibration procedures. We have exploited this characteristic for the in vivo detection of circulating gas emboli in an animal decompressed rapidly from a hyperbaric environment.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Franklin, D. L., Schlegel, W. A., and Rushmer, R. F., Science, 134, 564 (1961).

    Article  ADS  CAS  Google Scholar 

  2. Van Citters, R. L., and Franklin, D. L., Proc. Ann. Conf. on Eng. in Med. and Biol., 9, 27.7 (1967).

    Google Scholar 

  3. Gillis, M. F., Proc. Ann. Conf. on Eng. in Med. and Biol., 9, 33.6 (1967).

    Google Scholar 

  4. Strandness, jun., D. E., and Sumner, D. S., Proc. Ann. Conf. on Eng. in Med. and Biol., 9, 27.6 (1967).

    Google Scholar 

  5. Benchimol, A., Proc. Ann. Conf. on Eng. in Med. and Biol., 9, 27.6 (1967).

    Google Scholar 

  6. Bustad, L. K., Horstman, V. G., and England, D. C., in Swine in Biomedical Research, 769 (Battelle Memorial Institute, Pacific Northwest Laboratory, Richland, Washington, 1966).

    Google Scholar 

  7. Franklin, D. L., Watson, N. W., Pierson, K. E., and Van Citters, R. L., Amer. J. Med. Electronics, 5, 24 (1966).

    CAS  PubMed  Google Scholar 

  8. U.S. Navy Diving Manual, 1.6.2, NAVSHIPS 250–538 (Superintendent of Documents, US Government Printing Office, Washington, 1963).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

GILLIS, M., PETERSON, P. & KARAGIANES, M. In vivo Detection of Circulating Gas Emboli associated with Decompression Sickness using the Doppler Flowmeter. Nature 217, 965–967 (1968). https://doi.org/10.1038/217965a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/217965a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing