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Porphyrin Abiogenesis from Pyrrole and Formaldehyde under Simulated Geochemical Conditions

Abstract

Experiments with gas mixtures intended to simulate primeval atmospheres have yielded a great many types of chemicals of biological interest. It has now been shown that metal porphyrin complexes are commonly produced in these experiments.

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References

  1. Urey, H. C., in The Planets (Yale Univ. Press, New Haven, Conn., 1952).

    Google Scholar 

  2. Ponnamperuma, C., in Proc. Third Intern. Radiation Research Congress, Cortina, Italy (1966).

    Google Scholar 

  3. Miller, S. L., Science, 117, 528 (1953).

    Article  ADS  CAS  Google Scholar 

  4. Ponnamperuma, C., and Peterson, E., Science, 147, 1572 (1965).

    Article  ADS  CAS  Google Scholar 

  5. Harada, K., and Fox, S. W., in Origin of Prebiological Systems and of their Molecular Matrices (edit. by Fox, S. W.), 187 (Academic Press, New York, 1965).

    Book  Google Scholar 

  6. Fox, S. W., and Harada, K., Science, 128, 3333 (1958).

    Article  Google Scholar 

  7. Wilson, A. T., Nature, 188, 1007 (1960).

    Article  ADS  CAS  Google Scholar 

  8. Ponnamperuma, C., Lemmon, R. M., Mariner, R., and Calvin, M., Proc. Nat. Acad. Sci., 49, 737 (1963).

    Article  ADS  CAS  Google Scholar 

  9. Ponnamperuma, C., Young, R. S., Munoz, E. F., and McCaw, B. K., Science, 143, 1449 (1964).

    Article  ADS  CAS  Google Scholar 

  10. Ponnamperuma, C., Icarus, 5, 450 (1966).

    Article  ADS  CAS  Google Scholar 

  11. Oro, J., and Cox, A. C., Fed. Proc., 25, 80 (1962).

    Google Scholar 

  12. Ponnamperuma, C., and Kirk, P., Nature, 203, 400 (1964).

    Article  ADS  CAS  Google Scholar 

  13. Ponnamperuma, C., Sagan, C., and Mariner, R., Nature, 199, 222 (1963).

    Article  ADS  CAS  Google Scholar 

  14. Ponnamperuma, C., in Origins of Prebiological Systems and of their Molecular Matrices (edit. by Fox, S. W.), 221 (Academic Press, New York, 1965).

    Book  Google Scholar 

  15. Allen, W. V., and Ponnamperuma, C., Currents in Modern Biology, 1, 24 (1967).

    Google Scholar 

  16. Hodgson, G. W., and Baker, B. L., Nature, 202, 125 (1964).

    Article  ADS  CAS  Google Scholar 

  17. Marks, G. S., Ann. Rep. Chem. Soc., 59, 385 (1963).

    CAS  Google Scholar 

  18. Szutka, A., Nature, 212, 401 (1966).

    Article  ADS  CAS  Google Scholar 

  19. Chichibabin, A. E., J. Russ. Phys. Chem. Soc., 47, 703–13 (1965). See Chem. Abst., 9, 2512 (1915).

    Google Scholar 

  20. Rothemund, P., J. Amer. Chem. Soc., 58, 625 (1936).

    Article  CAS  Google Scholar 

  21. Hodgson, G. W., Baker, B. L., and Peake, E., in Fundamentals of Petroleum Geochemistry (edit. by Nagy, B., and Colombo, U.), 177–259 (Elsevier Publishing Co., 1967).

    Google Scholar 

  22. Hodgson, G. W., Baker, B. L., and Peake, E., Seventh World Petroleum Congress, Mexico City (1967).

    Google Scholar 

  23. Hodgson, G. W., Ushijima, N., Taguchi, K., and Shimada, I., Sci. Rept. Tohoku Univ., Series 3, 8, 483–513 (1963).

    CAS  Google Scholar 

  24. Fischer, H., and Stern, A., in Die Chemie des Pyrrols, 2, Part 2, 59 (Leipzig Akad. Verlagsges, 1940).

    Google Scholar 

  25. Falk, J. E., in Porphyrins and Metalloporphyrins (Elsevier, London, 1964).

    Google Scholar 

  26. Hodgson, G. W., and Hitchon, B., Bull. Amer. Soc. Petrol. Geol., 43, 2481 (1959).

    CAS  Google Scholar 

  27. Szutka, A., in Origin of Prebiological Systems and of their Molecular Matrices (edit. by Fox, S. W.), 243 (Academic Press, New York, 1965).

    Book  Google Scholar 

  28. Miller, S. L., J. Amer. Chem. Soc., 77, 2351 (1955).

    Article  CAS  Google Scholar 

Download references

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HODGSON, G., BAKER, B. Porphyrin Abiogenesis from Pyrrole and Formaldehyde under Simulated Geochemical Conditions. Nature 216, 29–32 (1967). https://doi.org/10.1038/216029a0

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