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Ultrastructure of the Membrane of Synaptic Vesicles

Abstract

INVESTIGATIONS by Whittaker and Sheridan1 on permanganate fixed preparations of isolated synaptic vesicles have recently confirmed that the membrane of such organelles has the structure of a “unit membrane”2, but have also indicated that in this case the classical model should be corrected in order to take into account the results obtained on negative stained specimens which suggest a membrane structure consisting of two 40 Å layers with an intermittent hydrophilic space between them.

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References

  1. Whittaker, V. P., and Sheridan, M. N., J. Neurochem., 12, 363 (1965).

    Article  CAS  Google Scholar 

  2. Robertson, J. D., in Regional Neurochemistry (edit. by Kety, L. L., and Elkes, J.), 497 (Pergamon Press, Oxford, 1961).

    Google Scholar 

  3. Sabatini, D. D., Bensch, K. G., and Barnett, R. J., J. Cell Biol., 17, 19 (1963).

    Article  CAS  Google Scholar 

  4. Luft, J. H., J. Biophys. Biochem. Cytol., 9, 409 (1961).

    Article  CAS  Google Scholar 

  5. Karnovsky, M. J., J. Biophys. Biochem. Cytol., 11, 729 (1961).

    Article  CAS  Google Scholar 

  6. Sjöstrand, F. L., Nature, 199, 1262 (1963).

    Article  ADS  Google Scholar 

  7. Sjöstrand, F. L., J. Ultrastruct. Res., 9, 340 (1963).

    Article  Google Scholar 

  8. Sjöstrand, F. L., and Elfvin, L. G., J. Ultrastruct. Res., 10, 263 (1964).

    Article  Google Scholar 

  9. Nilsson, S. E. G., Nature, 202, 509 (1964).

    Article  ADS  CAS  Google Scholar 

  10. Robertson, J. D., J. Cell Biol., 19, 201 (1963).

    Article  CAS  Google Scholar 

  11. Benedetti, E. L., and Emmelot, P., J. Cell Biol., 26, 299 (1965).

    Article  CAS  Google Scholar 

  12. Murray, R. G. E., cited by Kellenberger, E., and Ryter, A., in Modern Developments in Electron Microscopy (edit. by Siegel, B. M.), 373 (Academic Press, New York, 1964).

    Google Scholar 

  13. Luzzati, V., and Husson, F., J. Cell Biol., 12, 207 (1962).

    Article  CAS  Google Scholar 

  14. Stoeckenius, W., J. Cell Biol., 12, 221 (1962).

    Article  CAS  Google Scholar 

  15. Lucy, J. A., and Glauert, A. M., J. Mol. Biol., 8, 727 (1964).

    Article  CAS  Google Scholar 

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CARLO, V. Ultrastructure of the Membrane of Synaptic Vesicles. Nature 213, 833–835 (1967). https://doi.org/10.1038/213833b0

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