Abstract
THE efficiency of mutagenic agents is a complex value. It is not only dependent on the reactivity of the agent with the genetic material and on its applicability to a certain biological system, but also on the degree to which chromosome aberrations and other toxic effects are induced in addition to mutations. In order to examine the relationship between these forms of activity and to compare the efficiency of different mutagens, we have started investigations in which mutagenic agents are being tested for several biological effects under various treatment conditions in the same test system.
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References
Gichner, T., Michaelis, A., and Rieger, R., Biochem. Biophys. Res. Comm., 11, 120 (1963).
Green, M. O., and Greenberg, J., Cancer Res., 20, 1166 (1960).
Mandell, J. D., and Greenberg, J., Biochem. Biophys. Res. Comm., 3, 575 (1960).
Mandell, J. D., Woody, P. L., and Greenberg, J., J. Bact., 81, 419 (1961).
Müller, A. J., Biol. Zbl., 82, 133 (1963).
Müller, A. J., Proc. Symp. Induction of Mutation and Mutation Process (Praha, 1964).
Müller, A. J., Züchter, 34 (in the press).
Müller, A. J. (to be published).
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MÜLLER, A., GICHNER, T. Mutagenic Activity of 1-Methyl-3-nitro-1-nitrosoguanidine on Arabidopsis. Nature 201, 1149–1150 (1964). https://doi.org/10.1038/2011149b0
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DOI: https://doi.org/10.1038/2011149b0
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