Abstract
THE circulating platelet count of mice increases significantly after ultra-violet irradiation. Five to seven days after a single whole-body ultra-violet irradiation the increase is about 100 per cent. Para-biosis experiments, as well as the positive effect of isologous serum transfer, suggested that humoral factor(s) are responsible for the thrombocytopoietic effect and the agent seemed to be a protein-like macromolecule1 as already described for human serum2. In the present experiments we investigated the simultaneous action of whole-body X-ray irradiation, that is, a procedure causing severe thrombocytopenia, and ultra-violet radiation, that is, a procedure causing marked thrombocytosis.
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References
Cserháti, I., and Rák, K., Z. ges. exp. Med., 138, 38 (1958).
Rák, K., Cserháti, I., and Kelemen, E., Medicina Experimentalis, 1, 125 (1959).
Feissly, R., and Lüdin, H., Rev. Hématol., 4, 481 (1949).
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CSERHÁTI, I., KRIZSA, F. & RÁK, K. Circulating Platelets in Mice subjected to Simultaneous X-ray and Ultra-violet Irradiation. Nature 190, 544–545 (1961). https://doi.org/10.1038/190544b0
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DOI: https://doi.org/10.1038/190544b0
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