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Formation of β-Alanine from Spermine and Spermidine by Pseudomonas aeruginosa

Abstract

THE importance of β-alanine, especially as a constituent of pantothenic acid, in biological systems is well recognized; but little is known about its biosynthesis. One possible mechanism of formation involves the decarboxylation of aspartic acid though this has been established only for a small number of bacteria1. It has been recently found that β-alanine might also be formed from uracil by a certain species of Clostridium 2.

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References

  1. David, W. E., and Lichstein, H. C., Proc. Soc. Exp. Biol. Med., 73, 216 (1950).

    Article  CAS  Google Scholar 

  2. Campbell, jun., L. L., J. Bact., 73, 225 (1957).

    Article  CAS  Google Scholar 

  3. Razin, S., and Rozansky, R., J. Lab. Clin. Med., 49, 877 (1957).

    CAS  PubMed  Google Scholar 

  4. Miller, J. M., and Rockland, L. B., Arch. Biochem. Biophys., 40, 416 (1952).

    Article  CAS  Google Scholar 

  5. Decker, P., and Riffart, W., Chem. Z., 74, 261 (1950).

    CAS  Google Scholar 

  6. Bronk, J. R., and Fisher, R. B., Biochem. J., 164, 106 (1956).

    Article  Google Scholar 

  7. Hayaishi, O., “Methods in Enzymology”, edit. by Colowick, S. P., and Kaplan, N. O., 134 (Academic Press, New York, 1955).

    Google Scholar 

  8. Giri, K. V., Radhakrishnan, A. N., and Vaidyanathan, C., Nature, 170, 1025 (1952).

    Article  ADS  CAS  Google Scholar 

  9. Rosenthal, S. M., and Tabor, C. W., Pharm. Exp. Therap., 116, 131 (1956).

    CAS  Google Scholar 

  10. Tabor, H., Rosenthal, S. M., and Tabor, C. W., Fed. Proc., 15, 367 (1956).

    Google Scholar 

  11. Herbst, E. J., and Glinos, E. B., J. Biol. Chem., 214, 175 (1955).

    Article  CAS  Google Scholar 

  12. Martin, W. H., Pelczar, M. J., and Hansen, P. A., Science, 116, 483 (1952).

    Article  ADS  CAS  Google Scholar 

  13. Sneath, P. H. A., Nature, 175, 818 (1955).

    Article  ADS  CAS  Google Scholar 

Download references

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RAZIN, S., BACHRACH, U. & GERY, I. Formation of β-Alanine from Spermine and Spermidine by Pseudomonas aeruginosa . Nature 181, 700–701 (1958). https://doi.org/10.1038/181700a0

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