Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Vision

Dicer leaps into view

An enzyme called Dicer is known for its central role in RNA-controlled gene silencing. Mammalian Dicer1, however, also seems to have another function: it maintains visual health by degrading toxic RNA molecules. See Article p.325

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Geographic atrophy.

MICHAEL HANSON & BRADLEY GELFAND

References

  1. Jinek, M. & Doudna, J. A. Nature 457, 405–412 (2009).

    Article  CAS  ADS  Google Scholar 

  2. Zhang, H., Kolb, F. A., Jaskiewicz, L., Westhof, E. & Filipowicz, W. Cell 118, 57–68 (2004).

    Article  CAS  Google Scholar 

  3. Krol, J., Loedige, I. & Filipowicz, W. Nature Rev. Genet. 11, 597–610 (2010).

    Article  CAS  Google Scholar 

  4. Carthew, R. W. & Sontheimer, E. J. Cell 136, 642–655 (2009).

    Article  CAS  Google Scholar 

  5. Bartel, D. P. Cell 136, 215–233 (2009).

    Article  CAS  Google Scholar 

  6. Kaneko, H. et al. Nature 471, 325–330 (2011).

    Article  CAS  ADS  Google Scholar 

  7. Ambati, J., Ambati, B. K., Yoo, S. H., Ianchulev, S. & Adamis, A. P. Surv. Ophthalmol. 48, 257–293 (2003).

    Article  Google Scholar 

  8. Kim, V. N., Han, J. & Siomi, M. C. Nature Rev. Mol. Cell Biol. 10, 126–139 (2009).

    Article  CAS  Google Scholar 

  9. Lambertz, I. et al. Cell Death Differ. 17, 633–641 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Gunter Meister.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Meister, G. Dicer leaps into view. Nature 471, 308–309 (2011). https://doi.org/10.1038/471308a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/471308a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing