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Can peritoneal dialysis be used as a long term therapy for end stage renal disease?

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Abstract

Over the last 25 years, since the introductionof CAPD, the use of PD has increased greatlyand over this period many advances intechnique have been made. As is well known,that home and self-dialysis, such as PD, costless than in-center HD and can provideexcellent survival and a high level of patientrehabilitation. To date however, thedemonstration that PD can provide long termdialysis has been limited to a small number ofpatients.The next few decades will see a markedincrease in the worldwide dialysis population,particularly as older and sicker patients areaccepted into dialysis. It is likely thatworldwide pressures related to costcontainment will favour the use ofcost effective therapies, such as PD. However,the increased use of PD will continue, only ifwe continue to improve its efficacy and do notwaste the economic benefits gained over HD. Weare challenged to improve and develop PD in away that optimises patient medical andpsychosocial outcomes while minimizing costs.This may be achieved by using morebiocompatible solutions, hopefullyinexpensive, that will maintain the peritonealmembrane intact for long periods, will betterpreserve the membrane's transportcharacteristics over time, and thus reduce themain causes of drop out from dialysis.

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Authors and Affiliations

  1. Struttura Complessa di Nefrologia e Dialisi,Azienda USL Bari 5 Putignano, Italy

    Michele Giannattasio

  2. Cattedra di Nefrologia, Dipartimento di Medicina Interna, Università di Messina, taly

    Michele Buemi

  3. Unità Medica Trapianto di Rene, Ospedale Civico Palermo, Italy

    Flavia Caputo & Giusto Viglino

  4. Divisione di Nefrologia, Dialisi e Trapianto, Istituto G. Gaslini Genova, Italy

    Enrico Verrina

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  1. Michele Giannattasio
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  2. Michele Buemi
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  3. Flavia Caputo
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  4. Giusto Viglino
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  5. Enrico Verrina
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Correspondence to Michele Giannattasio.

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Giannattasio, M., Buemi, M., Caputo, F. et al. Can peritoneal dialysis be used as a long term therapy for end stage renal disease?. Int Urol Nephrol 35, 569–577 (2003). https://doi.org/10.1023/B:UROL.0000025644.90484.ec

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