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Tautomerism and Stereodynamics of Indophenols, Amidines, and Their Derivatives and Analogs: XVI. Synthesis of Tetrahydroquinoxalines Having Spiro-Fused Oxoindole and Cyclohepta[c]furan Fragments

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Abstract

Alkylation of o-(N-sulfonylamino)phenylimino derivatives of indol-2-one and cyclohepta[c]furan with phenacyl bromides is accompanied by cyclization to previously unknown tetrahydroquinoxalines having spiro-fused oxoindole and cyclohepta[c]furan fragments. The structure of the latter includes a nitrogen-oxygen triangular system typical of most natural cytotoxic compounds.

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Authors and Affiliations

  1. Rostov State University, Rostov-on-Don, Russia

    S. V. Kurbatov, D. N. Kuznetsov, V. I. Simakov, V. A. Voronina, Yu. A. Zhdanov & L. P. Olekhnovich

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  1. S. V. Kurbatov
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  2. D. N. Kuznetsov
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  3. V. I. Simakov
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  4. V. A. Voronina
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  5. Yu. A. Zhdanov
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  6. L. P. Olekhnovich
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Kurbatov, S.V., Kuznetsov, D.N., Simakov, V.I. et al. Tautomerism and Stereodynamics of Indophenols, Amidines, and Their Derivatives and Analogs: XVI. Synthesis of Tetrahydroquinoxalines Having Spiro-Fused Oxoindole and Cyclohepta[c]furan Fragments. Russian Journal of General Chemistry 74, 731–737 (2004). https://doi.org/10.1023/B:RUGC.0000039087.49416.5e

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  • DOI: https://doi.org/10.1023/B:RUGC.0000039087.49416.5e

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