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The Archaeal Signal Recognition Particle: Steps Toward Membrane Binding

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Abstract

Signal recognition particles and their receptors target ribosome nascent chain complexes of preproteins toward the protein translocation apparatus of the cell. The discovery of essential SRP components in the third urkingdom of the phylogenetic tree, the archaea (Woese, C. R., and Fox, G. E. (1977). Proc. Natl. Acad. Sci. U.S.A. 74, 5088–5090) raises questions concerning the structure and composition of the archaeal signal recognition particle as well as the functions that route nascent prepolypeptide chains to the membrane. Investigations of the archaeal SRP pathway could therefore identify novel aspects of this process not previously reported or unique to archaea when compared with the respective eukaryal and bacterial systems.

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References

  • Althoff, S., Selinger, D., and Wise, J. A. (1994). Nucleic Acids Res. 22, 1933-1947.

    Google Scholar 

  • Beck, K., Wu, L. F., Brunner, J., and Müller, M. (2000). EMBO J. 19, 134-143.

    Google Scholar 

  • Berks, B. C., Sargent, F., and Palmer, T. (2000). Mol. Microbiol. 35, 260-274.

    Google Scholar 

  • Bernstein, H. D., Poritz, M. A., Strub, K., Hoben, P. J., Brenner, S., and Walter, P. (1989). Nature 340, 482-486.

    Google Scholar 

  • Bhuiyan, S. H., Gowda, K., and Zwieb, C. (2000). Nucleic Acids Res. 28, 1365-1373.

    Google Scholar 

  • Connolly, T., and Gilmore, R. (1989). Cell 57, 599-610.

    Google Scholar 

  • Connolly, T., and Gilmore, R. (1993). J. Cell Biol. 123, 799-807.

    Google Scholar 

  • Connolly, T., Rapiejko, P. J., and Gilmore, R. (1991). Science 252, 1171-1173.

    Google Scholar 

  • Czarnota, G. J., Andrews, D. W., Farrow, N., and Ottensmeyer, F. P. (1994). J. Struct. Biol. 113, 35-46.

    Google Scholar 

  • Dale, H. C., Angevine, M., and Krebs, M. P. (2000). Proc. Natl. Acad. Sci. U.S.A. 97, 7847-7852.

    Google Scholar 

  • de Gier, J.-W., Mansournia, P., Valent, Q. A., Philipps, G. J., Luirink, J., and von Heijne, G. (1996). FEBS Lett. 399, 307-309.

    Google Scholar 

  • Dilks, K., Rose, R. W., Hartmann, E., and Pohlschröder, M. (2003). J. Bacteriol. 185, 1478-1483.

    Google Scholar 

  • Dobberstein, B. (1994). Nature 367, 599-600.

    Google Scholar 

  • Eichler, J. (2000). Eur. J. Biochem. 267, 3402-3412.

    Google Scholar 

  • Eichler, J., and Moll, R. (2001). Trends Microbiol. 9, 130-136.

    Google Scholar 

  • Gropp, R., Gropp, F., and Betlach, M. C. (1992). Proc. Natl. Acad. Sci. U.S.A. 89, 1204-1208.

    Google Scholar 

  • Hainzl, T., Huang, S., and Sauer-Eriksson, A. E. (2002). Nature 417, 767-771.

    Google Scholar 

  • Hershkowits, A. A., Bochkareva, E. S., and Bibi, E. (2000). Mol. Microbiol. 38, 927-939.

    Google Scholar 

  • Hershkovits, A. A., Shimoni, E., Minsky, A., Bibi, E. (2002). J. Cell Biol. 159, 403-410.

    Google Scholar 

  • Hirose, I., Sano, K., Shioda, I., Kumano, M., Nakamura, K., and Yamane, K. (2000). Microbiology 146, 65-75.

    Google Scholar 

  • Kalies, K.-U., Göhrlich, D., and Rapoport, T. (1994). J. Cell Biol. 126, 925-934.

    Google Scholar 

  • Keenan, R. J., Freymann, D. M., Stroud, R. M., and Walter, P. (2001). Annu. Rev. Biochem. 70, 755-775.

    Google Scholar 

  • Koch, H. G., Moser, M., and Müller, M. (2003). Rev. Physiol. Biochem. Pharmacol. 146, 55-94.

    Google Scholar 

  • Leeuw, E. D., Poland, D., Mol, O., Sinning, I., ten Hagen-Jongman, C. M., Oudega, B., Luirink, J., et al. (1997). FEBS Lett. 416, 225-229.

    Google Scholar 

  • Leeuw, E. D., te Kaat, K., Moser, C., Menestrina, G., de Kruijff, B., Oudega, B., Luirink, J., and Sinning, I. (2000). EMBO J. 19, 531-541.

    Google Scholar 

  • Leroux, M. R. (2001). Adv. Appl. Microbiol. 50, 219-277.

    Google Scholar 

  • Luirink, J., and Dobberstein, B. (1994). Mol. Microbiol. 11, 9-13.

    Google Scholar 

  • Luirink, J., ten Hagen-Jongman, C. M., van der Weijden, C. C., Oudega, B., High, S., Dobberstein, B., and Kusters, R. (1994). EMBO J. 13, 2289-2296.

    Google Scholar 

  • Lütcke, H. (1995). Eur. J. Biochem. 228, 531-550.

    Google Scholar 

  • Macao, B., Luirink, J., and Samuelsson, T. (1997). Mol. Microbiol. 24, 523-534.

    Google Scholar 

  • Maeshima, H., Okuno, E., Aimi, T., Morinaga, T., and Itoh, T. (2001). FEBS Lett. 507, 336-340.

    Google Scholar 

  • Miller, J. D., Tajima, S., Lauffer, L., and Walter, P. (1995). J. Cell Biol. 128, 273-282.

    Google Scholar 

  • Millman, J. S., and Andrews, D. W. (1997). Cell 89, 673-676.

    Google Scholar 

  • Moll, R., and Schäfer, G. (1988). FEBS Lett. 232, 359-363.

    Google Scholar 

  • Moll, R., Schmidtke, S., Petersen, A., and Schäfer, G. (1997). Biochim. Biophys. Acta 1335, 218-230.

    Google Scholar 

  • Moll, R., Schmidtke, S., and Schäfer, G. (1995). Biochim. Biophys. Acta 1261, 315-318.

    Google Scholar 

  • Moll, R., Schmidtke, S., and Schäfer, G. (1996). FEMS Microbiol. Lett. 137, 51-56.

    Google Scholar 

  • Moll, R., Schmidtke, S., and Schäfer, G. (1999). Eur. J. Biochem. 259, 441-448.

    Google Scholar 

  • Moll, R. G. (2003). Biochem. J. 374, 247-254.

    Google Scholar 

  • Montoya, G., Svensson, C., Luirink, J., and Sinning, I. (1997). Nature 385, 365-368.

    Google Scholar 

  • Montoya, G., te Kaat, K., Moll, R., Schäfer, G., and Sinning, I. (2000). Structure 8, 515-525.

    Google Scholar 

  • Moser, C., Mol, O., Goody, S., and Sinning, I. (1997). Proc. Natl. Acad. Sci. U.S.A. 94, 11339-11344.

    Google Scholar 

  • Nakamura, K., Yahagi, S., Yamuzaki, T., and Yamane, K. (1999). J. Biol. Chem. 274, 13569-13576.

    Google Scholar 

  • Newitt, J. A., and Bernstein, H. D. (1997). Eur. J. Biochem. 245, 720-729.

    Google Scholar 

  • Pohlschröder, M., Prinz, W. A., Hartmann, E., and Pohlschröder, M. (1997). Cell 91, 563-566.

    Google Scholar 

  • Prinz, A., Behrens, C., Rapoport, T. A., Hartmann, E., and Kalies, K. U. (2000). EMBO J. 19, 1900-1906.

    Google Scholar 

  • Ramirez, C., and Matheson, A. T. (1991). Mol. Microbiol. 5, 1687-1693.

    Google Scholar 

  • Rapiejko, P. J., and Gilmore, R. (1997). Cell 89, 703-713.

    Google Scholar 

  • Römisch, K., Webb, J., Lingelbach, K., Gausepohl, H., and Dobberstein, B. (1990). J. Cell Biol. 111, 1793-1802.

    Google Scholar 

  • Rose, R. W., Bruser, T., Kissinger, J. C., and Pohlschröder, M. (2002). Mol. Microbiol. 45, 943-950.

    Google Scholar 

  • Rose, R. W., and Pohlschröder, M. (2002). J. Bacteriol. 184, 3260-3267.

    Google Scholar 

  • Samuelsson, T. (1992). Nucleic Acids Res. 20, 5763-5770.

    Google Scholar 

  • Seluanov, A., and Bibi, E. (1997). J. Biol. Chem. 272, 2053-2055.

    Google Scholar 

  • Shepotinovskaya, I. V., and Freymann, D. M. (2002). Biochim. Biophys. Acta 1597, 107-114.

    Google Scholar 

  • Stephens, C. (1998). Curr. Biol. 8, 578-581.

    Google Scholar 

  • Stroud, R. M., and Walter, P. (1999). Curr. Opin. Struct. Biol. 9, 754-759.

    Google Scholar 

  • Tajima, S., Lauffer, L., Rath, V. L., and Walter, P. (1986). J. Cell Biol. 103, 1167-1178.

    Google Scholar 

  • Tozik, I., Huang, Q., Zwieb, C., and Eichler, E. (2002). Nucleic Acids Res. 30, 4166-4175.

    Google Scholar 

  • Ulbrandt, N. D., Newitt, J. A., and Bernstein, H. D. (1997). Cell 88, 187-196.

    Google Scholar 

  • Valent, Q. A., Scotti, P. A., High, S., de Gier, J.-W., von Heijne, G., Lentzen, G., Wintermeyer, W., Oudega, B., and Luirink, J. (1998). EMBO J. 17, 2504-2512.

    Google Scholar 

  • Walter, P., and Johnson, A. E. (1994). Annu. Rev. Cell Biol. 10, 87-119.

    Google Scholar 

  • Young, J. C., Ursini, J., Legate, K. R., Miler, J. D., Walter, P., and Andrews, D. W. (1995). J. Biol. Chem. 270, 15650-15657.

    Google Scholar 

  • Zheng, N., and Gierasch, L. M. (1997). Mol. Cell 1, 1-20.

    Google Scholar 

  • Zwieb, C., and Eichler, J. (2002). Archaea 1, 27-34.

    Google Scholar 

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  1. Department of Biochemistry, University of Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany; moll@biochem.uni-luebeck.de

    Ralf G. Moll

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Moll, R.G. The Archaeal Signal Recognition Particle: Steps Toward Membrane Binding. J Bioenerg Biomembr 36, 47–53 (2004). https://doi.org/10.1023/B:JOBB.0000019597.36170.5f

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