Abstract
Influence of the culture dish configuration on the millimeter-wave (MMW) irradiation distribution on the cell monolayer is analyzed for related bioelectromagnetic experiments. The MMW power density (PD), power absorption density (PAD) and specific absorption rate (SAR) are calculated with the finite-difference time-domain (FDTD) numerical technique and their distributions over the cell monolayer are displayed for the circular, square and combined culture dishes. As descriptions of the MMW irradiation uniformity on the cell monolayer, the mean, standard deviation (SD) and relative standard deviation (RSD) of the distributions are studied. Culture dishes of different configurations are recommended in different cases according to the radius of the cell monolayer to improve the irradiation uniformity since the influence of their configurations on the MMW irradiation distribution is significant.
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REFERENCES
A.G. Pakhomov, Y. Akyel, O.N. Pakhomova, et al. 1998. Current state and implications of research on biological effects of millimeter waves: A review of the literature. Bioelectromagnetics. 19(7):393-413.
E.R. Adair and R.C. Petersen. 2002. Biological effects of radio-frequency/microwave radiation. IEEE Transactions on Microwave Theory and Techniques. 50(3):953-962.
J.X. Zhao and Y. Li. 2001. Analysis of millimeter wave power density received by cell monolayers inside culture dishes. International Journal of Infrared and Millimeter Waves. 22(11):1577-1586.
J.X. Zhao. 2004. Improvement of MMW irradiation uniformity in culture dishes for experiments on MMW biological effects. Microwave and Optical Technology Letters. 40(3). In press.
H.Y. Chen and H.H. Wang. 1994 Current and SAR induced in a human head model by the electromagnetic fields irradiated from a cellular phone. IEEE Transactions on Microwave Theory and Techniques. 42(12):2249-2254.
A. Taflove. 1995. Computational Electrodynamics: The Finite-Difference Time-Domain Method. Boston: Artech House.
E. Li, W. Yuan and S. Wang. 2002. Signal propagation effects on high-speed interconnection lines using time-domain numerical technique. Microwave and Optical Technology Letters. 35(5):416-420.
G. Mur. 1981. Absorbing boundary conditions for the finite-difference approximation of the time-domain electromagnetic-field equations. IEEE Transactions on Electromagnetic Compatibility. 23(4):377-382.
J.S. Juntunen and T.D. Tsiboukis. 2000. Reduction of numerical dispersion in FDTD method through artificial anisotropy. IEEE Transactions on Microwave Theory and Techniques. 48(4):582-588.
C.D. Moss, F.L. Teixeira and J.A. Kong. 2002. Analysis and compensation of numerical dispersion in the FDTD method for layered, anisotropic media. IEEE Transactions on Antennas and Propagation. 50(9):1174-1184.
M. Burkhardt, K. Poković, M. Gnos, et al. 1996. Numerical and experimental dosimetry of Petri dish exposure setups. Bioelectromagnetics. 17(6):483-493.
J. Schuderer and N. Kuster. 2003. Effect of the meniscus at the solid/liquid interface on the SAR distribution in Petri dishes and flasks. Bioelectromagnetics. 24(2): 103-108.
J.X. Zhao and J.X. Li. 2003. Algorithm analysis of electromagnetic wave power density measurement for millimeter-wave irradiators in bioelectromagnetic experiments. International Journal of Infrared and Millimeter Waves. 24(6):909-928.
A.W. Guy and K.R. Foster. 1986. The microwave problem. Scientific American. 255(3):32-39.
K.R. Foster and W.F. Pickard. 1987. Microwaves: The risks of risk research. Nature. 330(6148):531-532.
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Zhao, J.X., Liu, D.G., Zhang, H.K. et al. Influence of Culture Dish Configuration upon MMW Irradiation Distribution on Cell Monolayer. International Journal of Infrared and Millimeter Waves 25, 413–426 (2004). https://doi.org/10.1023/B:IJIM.0000017909.73253.34
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DOI: https://doi.org/10.1023/B:IJIM.0000017909.73253.34