Abstract
Under normal thermal conditions, hypertensive NISAG rats are characterized by lower plasma levels of high-density lipoproteins and increased coefficient of atherogenicity compared to normotensive Wistar rats. Slow cooling significantly modified fractional composition of plasma lipoproteins in hypertensive rats: decreased the content of low-density lipoproteins, markedly increased the content of high-density lipoproteins, and normalized coefficient of atherogenicity. Our results demonstrated the possibility of correcting disturbances in lipoprotein spectrum in essential hypertension by using thermal exposures.
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Kozyreva, T.V., Lomakina, S.V., Tuzikov, F.V. et al. Slow Cooling Improved Blood Lipoprotein Composition in Hypertensive Rats. Bulletin of Experimental Biology and Medicine 136, 333–335 (2003). https://doi.org/10.1023/B:BEBM.0000010944.15030.5d
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DOI: https://doi.org/10.1023/B:BEBM.0000010944.15030.5d