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Ultrastructure of the Pineal Gland after γ-Irradiation under Conditions of Inhibition of Adrenocortical Function

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Abstract

Electron microscopy showed that whole-body γ-irradiation in sublethal doses led to the appearance of injuries in pinealocytes, glial cells, and vessels of the pineal gland in rats. Limitation of the nonspecific effect of γ-irradiation via inhibition of adrenocortical function with metopirone in physiological doses reduced the radiation-induced ultrastructural damage to the pineal gland.

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Authors and Affiliations

  1. Medical Radiology Research Center, Russian Academy of Medical Sciences, Obninsk

    V. V. Popuchiev, N. D. Yakovleva, A. G. Konoplyannikov, I. M. Kvetnoi, K. Kita & I. Kita

  2. North-Western Division of Russian Academy of Medical Sciences, St. Petersburg Institute of Bioregulation and Gerontology, Russia

    V. V. Popuchiev, N. D. Yakovleva, A. G. Konoplyannikov, I. M. Kvetnoi, K. Kita & I. Kita

  3. Institute of Industrial Organic Chemistry, Poland

    V. V. Popuchiev, N. D. Yakovleva, A. G. Konoplyannikov, I. M. Kvetnoi, K. Kita & I. Kita

Authors
  1. V. V. Popuchiev
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  2. N. D. Yakovleva
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  3. A. G. Konoplyannikov
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  4. I. M. Kvetnoi
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  5. K. Kita
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  6. I. Kita
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Correspondence to V. V. Popuchiev.

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Popuchiev, V.V., Yakovleva, N.D., Konoplyannikov, A.G. et al. Ultrastructure of the Pineal Gland after γ-Irradiation under Conditions of Inhibition of Adrenocortical Function. Bulletin of Experimental Biology and Medicine 135, 603–607 (2003). https://doi.org/10.1023/A:1025402007545

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  • DOI: https://doi.org/10.1023/A:1025402007545

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