Abstract
The role of serotonin in the membrane properties of identified neurons was studied during acquisition of a conditioned defensive reflex. Serotonin deficiency was created using the neurotoxic serotonin analog 5,6-dihydroxytryptamine (5,6-DHT). Injection of 5,6-DHT was found to prevent decreases in the membrane and threshold potentials of command neurons during acquisition of the conditioned reflex as compared with snails given 5,6-DHT without training. Common snails recovered the ability to acquire the conditioned reflex two weeks after a second 5,6-DHT injection.
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Gainutdinova, T.K., Andrianov, V.V. & Gainutdinov, K.L. Electrophysiological Studies of the Effects of 5,6-Dihydroxytryptamine on the Acquisition of a Conditioned Defensive Reflex in Snails. Neurosci Behav Physiol 33, 623–627 (2003). https://doi.org/10.1023/A:1023943006652
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DOI: https://doi.org/10.1023/A:1023943006652