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Investigation of the Reaction of 3,5-Diamidino-4-nitropyrazole with Amines

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The interaction of 3,5-bis(N,N-dimethylaminomethylene)amino-1-methyl-4-nitropyrazole with amines proceeds regioselectively with the formation of 3-amino-5-(N,N-dimethylaminomethylene)amino-1-methyl-4-nitropyrazole. Amines are converted in this way into N,N-dimethylformamidine derivatives. The structures of the compounds obtained were proved by 1H and 13C NMR spectroscopy and by X-ray crystallographic analysis.

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Makarov, V.A., Ryabova, O.B., Alekseeva, L.M. et al. Investigation of the Reaction of 3,5-Diamidino-4-nitropyrazole with Amines. Chemistry of Heterocyclic Compounds 38, 947–953 (2002). https://doi.org/10.1023/A:1020921530209

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  • DOI: https://doi.org/10.1023/A:1020921530209

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