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Antioxidant Activity of Blood Plasma in Individuals with Neoplasms

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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

In 3 groups of patients with neoplasms plasma antioxidant activity was measured by the yield of TBA-reactive products generated in lecithin-Fe2+ model system. Patients with laryngeal, tongue, oropharyngeal, oral, and laryngopharyngeal tumors showed lower plasma antioxidant activity compared to patients with breast, lung, and bronchial cancer (p<0.005). In women with breast cancer plasma antioxidant activity increased with age (p<0.05). Possible mechanisms underlying these fluctuations are discussed. It is assumed that plasma antioxidant activity is relatively stable and modulates body resistance to tumor process.

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Authors and Affiliations

  1. Institute of Medical Genetics, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Russia

    A. V. Marusin, V. B. Salyukov & E. Yu. Bragina

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  1. A. V. Marusin
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  2. V. B. Salyukov
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  3. E. Yu. Bragina
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Correspondence to A. V. Marusin.

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Marusin, A.V., Salyukov, V.B. & Bragina, E.Y. Antioxidant Activity of Blood Plasma in Individuals with Neoplasms. Bulletin of Experimental Biology and Medicine 133, 481–483 (2002). https://doi.org/10.1023/A:1019869922937

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