Abstract
The complete sequence (28580 nt) of the PUR46-MAD clone of the Purdue cluster of transmissible gastroenteritis coronavirus (TGEV) has been determined and compared with members of this cluster and other coronaviruses. The computing distances among their S gene sequences resulted in the grouping of these coronaviruses into four clusters, one of them exclusively formed by the Purdue viruses. Three new potential sequence motifs with homology to the α-subunit of the polymerase-associated nucleocapsid phosphoprotein of rinderpest virus, the Bowman–Birk type of proteinase inhibitors, and the metallothionein superfamily of cysteine rich chelating proteins have been identified. Comparison of the TGEV polymerase sequence with that of other RNA viruses revealed high sequence homology with the A–E domains of the palm subdomain of nucleic acid polymerases.
Article PDF
Similar content being viewed by others
Avoid common mistakes on your manuscript.
References
Almazan F., González J.M., Pénzes Z., Izeta A., Calvo E., Plana-Durán J., and Enjuanes L., Proc Natl Acad Sci USA 97, 5516-5521, 2000.
Ballesteros M.L., Sánchez C.M., and Enjuanes L., Virology 227, 378-388, 1997.
Baric R.S. and Yount B., J Virol 74, 4039-4046, 2000.
Bernard S. and Laude H., J Gen Virol 76, 2235-2241, 1995.
Bohl E.H. and Cross R.F., Ann NY Acad Sci 176, 150-161, 1971.
Bohl E.H., Gupta P., Olquin F., and Saif L.J., Infect Immun 6, 289-301, 1972.
Bohl E.H. and Kumagai T., Proceedings United States Livestock Sanitary Association 69, 343-350, 1965.
Boursnell M.E.G., Brown T.D.K., Foulds I.J., Green P.F., Tomley F.M., and Binns M.M., J Gen Virol 68, 57-77, 1987.
Brian D.A., Dennis D.E., and Guy J.S., J Virol 34, 410-415, 1980.
Britton P., Mawditt K.L., and Page K.W.,Virus Res 21, 181-198, 1991.
Chen C.-M., Cavanagh D., and Britton P., Vir Res 38, 83-89, 1995.
Domingo E. and Holland J.J., The Evolutionary Biology of Viruses-Mutation Rates and Rapid Evolution of RNA Viruses.Raven Press, New York, 1994.
Eleouet J.F., Rasschaert D., Lambert P., Levy L., Vende P., and Laude H., Virology 206, 817-822, 1995.
Eleouet J.F., Slee E.A., Saurini F., Castagne N., Poncet D., Garrido C., Solary E., and Martin S.J., J Virol 74, 3975-3983, 2000.
Enjuanes L., Brian D., Cavanagh D., Holmes K., Lai M.M.C., Laude H., Masters P., Rottier P., Siddell S.G., Spaan W.J.M., Taguchi F., and Talbot P., Virus Taxonomy. Classification and Nomenclature of Viruses-Coronaviridae. Academic Press, New York, 2000a.
Enjuanes L., Siddell S.G., and Spaan W.J., Coronaviruses and Arteriviruses. Plenum Press, New York, 1998.
Enjuanes L., Spaan W., Snijder E., and Cavanagh D., Virus Taxonomy. Classification and Nomenclature of Viruses-Nidovirales. Academic Press, New York, 2000b.
Escors D., Ortego J., Laude H., and Enjuanes L., J Virol 75, 1312-1324, 2001.
Fichot O. and Girard M., Nucleic Acids Res 18, 6162, 1990.
French R. and Ahlquist P., J Virol 62, 2411-2420, 1988.
Gebauer F., Posthumus W.A.P., Correa L., Suñé C., Sánchez C.M., Smerdou C., Lenstra J.A., Meloen R., and Enjuanes L., Virology 183, 225-238, 1991.
Gorbalenya A.E., Koonin E.V., Donchenko A.P., and Blinov V.M., Nucleic Acids Res. 17, 4847-4861, 1989.
Haelterman E.O. and Pensaert M.B., Pathogenesis of transmissible gastroenteritis of swine, Proc 18thWorld Vet Congress, Paris 1967.
Hansen J.L., Long A.M., and Schultz S.C., Structure 5, 1109-1122, 1997.
Harmon S.B., Megaw G., and Wertz G.W., J Virol 75, 36-44, 2001.
Herold J., Raabe T., Schelle-Prinz B., and Siddell S.G., Virology 195, 680-691, 1993.
Higgins D.G., Thompson J.D., and Gibson T.J., Meth Enzymol 266, 383-402, 1996.
Hofmann M.A. and Brian D.A., J Virol 65, 6331-6333, 1991.
Iverson L.E. and Rose J.K., Cell 23, 477-484, 1981.
Izeta A., Smerdou C., Alonso S., Penzes Z., Méndez A., Plana-Durán J., and Enjuanes L., J Virol 73, 1535-1545, 1999.
Jiménez G., Correa L, Melgosa M.P., Bullido M.J., and Enjuanes L., J Virol 60, 131-139, 1986.
Kapke P.A. and Brian D.A., Virology 151, 41-49, 1986.
Lai M.M.C., Brayton P.R., Armen R.C., Patton C.D., Pugh C., and Stohlman S.A., J Virol 39, 823-834, 1981.
Lai M.M.C. and Cavanagh D., Adv Virus Res 48, 1-100, 1997.
Laude H. and Masters P.S., The Coronaviridae-The Coronavirus Nucleocapsid Protein. Plenum press, New York, 1995.
Laude H., Vanreeth K., and Pensaert M., Vet Res 24, 125-150, 1993.
Lee H.J., Shieh C.K., Gorbalenya A.E., Koonin E.V., Lamonica N., Tuler J., Bagdzhadzhyan A., and Lai M.M.C., Virology 180, 567-582, 1991.
Lee K.M., Moro M., and Baker J.A., Amer JVet Res 15, 364-372, 1954.
McClurkin A.W. and Norman J.O., Can J Comp Med Vet Sci 30, 190-198, 1966.
Méndez A., Smerdou C., Izeta A., Gebauer F., and Enjuanes L., Virology 217, 495-507, 1996.
Mizutani T., Repass J.F., and Makino S.,Virology 275, 238-243, 2000.
Murthy H.M., Judge K., DeLucas L., and Padmanabhan R., JMol Biol 301, 759-767, 2000.
O'Reilly E.K. and Kao C.C., Virology 252, 287-303, 1998.
Pachuk C.J., Bredenbeek P.J, Zoltick P.W., Spaan W.J.M., and Weiss S., Virology 171, 141-148, 1989.
Penzes Z., González J.M., Izeta A., Muntion M., and Enjuanes L., Adv Exp Med Biol 440, 319-327, 1998.
Rasschaert D., Gelfi J., and Laude H., Biochimie 69, 591-600, 1987.
Register K.B. and Wesley R.D., J Vet Diagn Invest 6, 16-22, 1994.
Rohrmeier T. and Lehle L., Plant Mol Biol 22, 783-792, 1993.
Sambrook J., Fritsch E.F., and Maniatis T., Molecular Cloning: A Laboratory Manual. 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1989.
Sánchez C.M., Gebauer F., Suñé C., Méndez A., Dopazo J., and Enjuanes L., Virology 190, 92-105, 1992.
Sánchez C.M., Izeta A., Sánchez-Morgado J.M., Alonso S., Sola L, Balasch M., Plana-Duran J., and Enjuanes L., J Virol 73, 7607-7618, 1999.
Sawicki S.G. and Sawicki D.L., J Virol 64, 1050-1056, 1990.
Sawicki S.G. and Sawicki D.L., Adv Exp Med Biol 440, 215-220, 1998.
Sethna P.B., Hofmann M.A., and Brian D.A., J Virol 65, 320-325, 1991.
Sethna P.B., Hung S.-L., and Brian D.A., Proc Natl Acad Sci USA 86, 5626-5630, 1989.
Spagnolo J.F. and Hogue B.G., J Virol 74, 5053-5065, 2000.
Stephensen C.B., Casebolt D.B., and Gangopadhyay N.N.,Virus Res 60, 181-189, 1999.
Thiel V., Herold J., and Siddell S., Nidovirus: Coronavirus and Arterivirus-Full-Length Genomic Sequence of Bovine Coronavirus. Kluwer Academic/Plenum Publishers, New York, 2001.
Thompson J.D., Gibson T.J., Plewniak F., Jeanmougin F., and Higgins D.G., Nucleic Acids Res 24, 4876-4882, 1997.
Thompson J.D., Higgins D.G., and Gibson T.J., Nucleic Acids Res 22, 4673-4680, 1994.
van der Most R.G. and Spaan W.J.M., The Coronaviridae-Coronavirus Replication, Transcription, and RNA Recombination.Plenum Press, New York, 1995.
van Marle G., Dobbe J.C., Gultyaev A.P., Luytjes W., Spaan W.J.M., and Snijder E.J., Proc Nat Acad Sci USA 96, 12056-12061, 1999.
Vaughn R.M., Halbur P.G., and Paul P.S., J Virol 69, 3176-3184, 1995.
Wertz G.W., Perepelitsa V.P., and Ball L.A., Proc Natl Acad Sci USA 95, 3501-3506, 1998.
Wesley R.D., Cheung A.K., Michael D.M., and Woods R.D., Virus Res 13, 87-100, 1989.
Wesley R.D., Woods R.D., and Cheung A.K., J Virol 64, 4761-4766, 1990.
Wesley R.D., Woods R.D., and Cheung A.K., J Virol 65, 3369-3373, 1991.
Whitelaw C.A., Le Huquet J.A., Thurman D.A., and Tomsett A.B., Plant Mol Biol 33, 503-511, 1997.
Yamanaka M., Dale B., Crisp T., Cordell B., Crubman M., and Yilma T., Virology 190, 553-556, 1992.
Yogo Y., Hirano N., Hino S., Shibuta H., and Matumoto M., J Biochem 82, 1103-1108, 1977.
Yoo D. and Pei Y., Nidovirus: Coronavirus and Arterivirus-Full-Length Genomic Sequence of Bovine Coronavirus. Kluwer Academic/Plenum Publishers, New York, 2001.
Yount B., Curtis K.M., and Baric R.S., J Virol 74, 10600-10611, 2000.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Penzes, Z., González, J.M., Calvo, E. et al. Complete Genome Sequence of Transmissible Gastroenteritis Coronavirus PUR46-MAD Clone and Evolution of the Purdue Virus Cluster. Virus Genes 23, 105–118 (2001). https://doi.org/10.1023/A:1011147832586
Issue Date:
DOI: https://doi.org/10.1023/A:1011147832586