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Development of ERG responses: The ISCEV rod, maximal and cone responses in normal subjects

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Abstract

Purpose: Summarize ISCEV ERG responses from normal infants and children. Methods: The amplitudes and implicit times of the ISCEV rod, maximal dark-adapted and cone responses from a total of 409 normal infants (n=128), children and adult controls were compiled. The subjects, aged 1 week to 52 years, were divided into seven age groups, including four in infancy (<52 weeks). The response parameters for each age group were summarized as percentiles. Results: In each ISCEV condition, the youngest infants (1–5 weeks) had significantly smaller amplitudes and longer implicit times than adults. Amplitude increased and implicit time decreased systematically with age. Conclusions: The developmental changes in ERG responses are significant. The medians and ranges herein provide provisional norms against which the ERG responses from pediatric patients can be compared

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Fulton, A.B., Hansen, R.M. & Westall, C.A. Development of ERG responses: The ISCEV rod, maximal and cone responses in normal subjects. Doc Ophthalmol 107, 235–241 (2003). https://doi.org/10.1023/B:DOOP.0000005332.88367.b8

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  • DOI: https://doi.org/10.1023/B:DOOP.0000005332.88367.b8

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