Abstract
We have developed a range of glucose sensing contact lenses, using a daily, disposable contact lens embedded with newly developed boronic acid containing fluorophores. Our findings show that our approach may be suitable for the continuous monitoring of tear glucose levels in the range 50–1000 μM, which typically track blood glucose levels, which are ≈5–10 fold higher. Our non-invasive approach may well offer an alternative solution to current invasive glucose monitoring techniques for diabetes, such as “finger pricking.”
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Badugu, R., Lakowicz, J.R. & Geddes, C.D. A Glucose Sensing Contact Lens: A Non-Invasive Technique for Continuous Physiological Glucose Monitoring. Journal of Fluorescence 13, 371–374 (2003). https://doi.org/10.1023/A:1026103804104
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DOI: https://doi.org/10.1023/A:1026103804104