Skip to main content
Log in

A New Therapeutic Approach for Treatment of Hydatid Cysts of the Spleen

  • Published:
Digestive Diseases and Sciences Aims and scope Submit manuscript

Abstract

The aims of this study were to investigate the efficacy of a new percutaneous treatment of hydatid cysts of the spleen and to present the results of long-term follow-up. Nine patients (six men, three women; median age 37 years) with 10 hydatid cysts in the spleen underwent a new percutaneous treatment. The procedure included the puncture and free drainage of the cyst fluid under sonographic guidance. After drainage has stopped, alcohol 96% and polidocanol 1% were used as sclerosing agents. The patients were followed up with periodic sonographic examinations. The median follow-up period was 39 months (range: 6–64 months). The median diameter of the cysts decreased from 63.0 mm to 33.3 mm (P < 0.01). The entire cyst cavity filled with a solid echo pattern in three cysts, two thirds of the cyst cavity showed a pseudotumor pattern in three cysts, and one third of the cyst cavity showed a pseudotumor pattern in four cysts. Apart from an urticarial reaction, no major complications occurred during the follow-up period. One patient had under-gone splenectomy due to persistent left upper quadrant pain eight months after treatment. Long-term results indicate that this new treatment modality of splenic hydatidosis is an effective and safe method and causes no major complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Dawson H. Stamatakis JD, Stringer MD, Williams R: Surgical treatment of hepatic hydatid disease. Br J Surg 75:946–950, 1988

    Google Scholar 

  2. Zmerli S, Ayed M, Horchani A, Chami I, Oualcdi ME, Slama MRB: Hydatid disease of the kidney: Diagnosis and treatment. World J Surg 35:68–74, 2001

    Google Scholar 

  3. Barros JL: Hydatid disease of the liver. Am J Surg 79:597–600, 1978

    Google Scholar 

  4. Lewis JW, Koss N, Kerstein MD: A review of echinococcal disease. Ann Surg 181:390–396, 1975

    Google Scholar 

  5. Lygidakis NJ: Diagnosis and treatment of intrabiliary rupture of hydatid cyst of the liver. Arch Surg 118:1186–1189, 1983

    Google Scholar 

  6. Kune GA, Jones T, Sali A: Hydatid disease in Australia: Prevention, clinical complications and treatment. Med J Aust 3:385–388, 1983

    Google Scholar 

  7. Beggs I: The radiological appearances of hydatid disease of the liver. Clin Radiol 34:555–563, 1983

    Google Scholar 

  8. Gürses N, Sungur R, Gürses N, Ozkan K: Ultrasound diagnosis of liver hydatid disease. Acta Radiol 28:161–163, 1987

    Google Scholar 

  9. Safioleas M, Misiakos E, Manti C: Surgical treatment for splenic hydatidosis. World J Surg 21:374–378, 1997

    Google Scholar 

  10. Manouras AJ, Nikolaou CC, Katergiannakis VA, Apostolidis NS, Golematis BC: Spleen-sparing surgical treatment for echinococcosis of the spleen. Br J Surg 84:1162, 1997

    Google Scholar 

  11. Khoury G, Abiad F, Geagea T, Nabout G, Jabbour S: Laparoscopic treatment of hydatid cysts of the liver and spleen. Surg Endosc 14:243–245, 2000

    Google Scholar 

  12. Morris DL: The use of albendazole in human hydatid disease. Ann Trop Med Parasitol 78:204–205, 1984

    Google Scholar 

  13. Todorov T, Vutova K, Mechkov G, Petkov D, Nedelkov G, Tonchev Z: Evaluation of response to chemotherapy of human cystic echinococcus. Br J Radiol 63:523–531, 1990

    Google Scholar 

  14. Vutova K, Mechkov G, Vachkov P, Petkov R, Georgiev P, Handjiev S, Ivanov A, Todorov T: Effect of mebendazole on human cystic echinococcosis: The role of dosage and treatment duration. Ann Trop Med Parasitol 93:357–365, 1999

    Google Scholar 

  15. Bastid C, Azar C, Doyer M, Sahel J: Percutaneous treatment of hydatid cysts under sonographic guidance. Dig Dis Sci 39:1576–1580, 1994

    Google Scholar 

  16. Akhan O, Özmen MN, Dinçer A, Sayek I, Göçmen A: Liver hydatid disease: Long-term results of percutaneous treatment. Radiology 198:259–264, 1996

    Google Scholar 

  17. Men S, Hekimoglu B, Yücesoy C, Arda S, Baran I: Percutaneous treatment of hepatic hydatic cysts: an alternative to surgery. AJR 172:83–89, 1999

    Google Scholar 

  18. Ñstünsöz B, Akhan O, Kamiloğlu MA, Somuncu I, Uğurel MS, Çetiner S: Percutaneous treatment of hydatid cysts of the liver: Long-term results. AJR 172:91–96, 1999

    Google Scholar 

  19. Gharbi HA, Hanine W, Brauner MW, Dupuch K: Ultrasound examination of the hydatic liver. Radiology 139:459–463, 1981

    Google Scholar 

  20. Gade J, Brasso K, Junge J, Olesen HP: Pleurodesis with polidocanol in pigs: an experimental study. Chest 105:908–910, 1994

    Google Scholar 

  21. De la Pena J, Rivero M, Sanchez E, Fabrega E, Crespo J, Pons-Romero F: Variceal ligation compared with endoscopic sclerotherapy for variceal hemorrhage: prospective randomized trial. Gastrointest Endosc 49:417–423, 1999

    Google Scholar 

  22. Akhan O, Dinçer A, Gökoz A, Sayek I, Havlioğlu S, Abbasoğlu O, Erytlmaz M, Besim A, Baris I: Percutaneous treatment of abdominal hydatic cysts with hypertonic saline and alcohol: An experimental study in sheep. Invest Radiol 28:121–127, 1993

    Google Scholar 

  23. Saimot AG, Meulemans A, Cremieux AC, Giovanangeli MD, Hay JM, Delaitre B, Coulaud JP: Albendazole as a potential treatment for human hydatidosis. Lancet 2:652–656, 1983

    Google Scholar 

  24. Saimot AG: Medical treatment of liver hydatidosis. World J Surg 25:15–20, 2001

    Google Scholar 

  25. Bezzi M, Teggi A, DeRosa FD, Capozzi A, Tucci G, Bunifacino A, Angelini L: Abdominal hydatid disease: US findings during medical treatment. Radiology 162:91–95, 1987

    Google Scholar 

  26. Muller PR, Dawson SL, Ferucci J: Hepatic echinococcal cyst, succesful percutaneous drainage, Radiology 155:627–628, 1985

    Google Scholar 

  27. Filice C, Pirola F, Brunetti E, Dughetti S, Stroselli M, Foglieni CS: A new therapeutic approach for hydatid liver cysts: aspiration and alcohol injection under sonographic guidance. Gastroenterology 98:1366–1368, 1990

    Google Scholar 

  28. Akhan O, Çekirge S, Özmen MN, Besim A: Percutaneous transcatheter sclerotherapy of postoperative pelvic lymphoceles. Cardiovasc Intervent Radiol 15:224–227, 1992

    Google Scholar 

  29. Crosby WH: The hematopoietic system. In Gastroenterology, Vol 4, 5th ed. WS Haubrich, F Schaffner, JE Berk (eds). Philadelphia, WB Saunders, 1995, pp 3420–3432

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Örmeci, N., Soykan, I., Palabiyikoglu, M. et al. A New Therapeutic Approach for Treatment of Hydatid Cysts of the Spleen. Dig Dis Sci 47, 2037–2044 (2002). https://doi.org/10.1023/A:1019672828967

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/A:1019672828967

Navigation