Abstract
Bioabsorbable polymers are of interest as internal fracture fixation devices. Self-reinforcement has been developed to improve the mechanical properties of the material and the addition of calcium phosphate fillers improves the bioactivity. Composite plates, produced by compression molding preimpregnated sheets of polylactide fibers coated in a polylactide matrix have been degraded in simulated body fluid for up to 12 weeks. Some samples also contained hydroxyapatite or tricalcium phosphate filler particles. Degradation was measured by monitoring the water uptake and mass decrease of the samples, as well as carrying out four point bend tests to assess the mechanical properties of the material. By 12 weeks, it was found that the unfilled samples absorbed more water and showed greater mass loss than the samples containing calcium phosphate fillers. Also, the flexural modulus and yield stress decreased significantly at week 12 for the unfilled samples. Adding hydroxyapatite (HA) or tricalcium phosphate (TCP) to the composite increased the flexural modulus and yield strength to values within the range of those reported for cortical bone and these values were maintained over the 12-week period.
© 2001 Kluwer Academic Publishers
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
P. Rokkanen, S. VainionpÄÄ, K. Vihtonen, P. TÖrmÄlÄ, J. Laiho, J. Kilpikari, M. TamminmÄki and O. BÖstman, The Lancet 2 (1985) 1422.
P. TÖrmÄlÄ, T. Pohjonen and P. Rokkanen, Proc. Instn. Mech. Engrs. 212-H (1998) 101.
L. E. Claes, Clin. Mater. 10 (1992) 41.
P. TÖrmÄlÄ, ibid. 10 (1992) 29.
P. TÖrmÄlÄ, P. Rokkanen, J. Laiho and S. VainionpÄÄ, US Patent No. 4743257 (1998).
M. Dauner, H. Planck, L. Caramaro, Y. Missirlis and E. Panagiotopoulos, J. Mater. Sci: Mater. Med. 9 (1998) 173.
C. C. P. M. Verheyen, J. R. De Wijn, C. A. Van Blitterswijk and K. De Groot, J. Biomed. Mater. Res. 26 (1992) 1277.
M. Kikuchi, Y. Suetsugu, J. Tanka and M. Akao, J. Mater. Sci.: Mater. Med. 8 (1997) 361.
C. C. P. M. Verheyen, J. R. De Wijn, C. A. Van Blitterswijk, K. De Groot and P. M. Rozing, J. Biomed. Mater. Res. 27 (1993) 433.
T. Yasunaga, Y. Matsusue, T. Furukawa, Y. Shikinami, M. Okuno and T. Nakamura, ibid. 47 (1999) 412.
M. KellomÄki, K. E. Tanner, W. Bonfield and P. TÖrmÄlÄ, in “Proceedings of the 13th European Conference on Biomaterials”, 1997, p. 90.
P. TÖrmÄlÄ, M. KellomÄki, W. Bonfield and K. E. Tanner, US Patent Appl. No. 08/921,533 (1997).
T. Kokubo, H. Kushitani, S. Sakka, T. Kitsugi and T. Yamamuro, J. Biomed. Mater. Res. 24 (1990) 721.
T. Nakamura, S. Hitomi, S. Watanabe, Y. Shimizu, K. Jamshidi, S.-H. Hyon and Y. Ikada, ibid. 23 (1989) 1115.
Y. Matsusue, T. Yamamuro, M. Oka, Y. Shikinami, S.-H. Hyon and Y. Ikada, ibid. 26 (1992) 1553.
H. Oonishi and K. Oomamiuda, in “Handbook of Biomaterial Properties”, edited by J. Black and G. Hastings (Chapman & Hall, London, 1998) p. 406.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bleach, N.C., Tanner, K.E., Kellomäki, M. et al. Effect of filler type on the mechanical properties of self-reinforced polylactide–calcium phosphate composites. Journal of Materials Science: Materials in Medicine 12, 911–915 (2001). https://doi.org/10.1023/A:1012884310027
Issue Date:
DOI: https://doi.org/10.1023/A:1012884310027