Abstract
An agar diffusion bioassay was used to compare the sensitivities of bacteria to the mycotoxin beauvericin. Bacillus pumilus LACB101 was inhibited by filter-paper disks containing 0.1 μg of beauvericin; B. cereus, B. mycoides, B. sphaericus, Paenibacillus alvei, P. azotofixans, P. macquariensis, and P. pulvifaciens by 1 μg; and P. validus by 25 μg. The anaerobes Eubacterium biforme, Peptostreptococcus anaerobius, P. productus, Bifidobacterium adolescentis, and Clostridium perfringens were also inhibited by beauvericin.
This is a preview of subscription content, log in via an institution to check access.
References
Becker, B., Bresch, H., Schillinger, U. & Thiel, P.G. 1997 The effect of fumonisin B1 on the growth of bacteria. World Journal of Microbiology and Biotechnology 13, 539–543.
Champlin, F.R. & Grula, E.A. 1979 Noninvolvement of beauvericin in the entomopathogenicity of Beauveria bassiana. Applied and Environmental Microbiology 37, 1122–1125.
Conway, P.L. 1995 Microbial ecology of the human large intestine. In: Human colonic bacteria: Role in nutrition, physiology, and pathology, ed. Gibson, G.R. & Macfarlane, G.T. pp. 1–17. Boca Raton, Florida. CRC Press. ISBN 0-8493-4524-3.
Grove, J.F. & Pople, M. 1980 The insecticidal activity of beauvericin and the enniatin complex. Mycopathologia 70, 103–105.
Hamill, R.L., Higgens, C.E., Boaz, H.E. & Gorman, M. 1969 The structure of beauvericin, a new depsipeptide antibiotic toxic to Artemia salina. Tetrahedron Letters 49, 4255–4258.
Krska, R., Schuhmacher, R., Grasserbauer, M. & Scott, P.M. 1996 Determination of the Fusarium mycotoxin beauvericin at μ/kg levels in corn by high-performance liquid chromatography with diode-array detection. Journal of Chromatography A 746, 233–238.
Logrieco, A., Moretti, A., Ritieni, A., Chelkowski, J., Altomare, C., Bottalico, A. & Randazzo, G. 1993 Natural occurrence of beauvericin in preharvest Fusarium subglutinans infected corn ears in Poland. Journal of Agricultural and Food Chemistry 41, 2149–2152.
Madhyastha, M.S., Marquardt, R.R., Masi, A., Borsa, J. & Frohlich, A.A. 1994 Comparison of toxicity of different mycotoxins to several species of bacteria and yeasts: Use of Bacillus brevis in a disc diffusion assay. Journal of Food Protection 57, 48–53.
Ojcius, D.M., Zychlinsky, A., Zheng, L.M. & Young, J.D.-E. 1991 Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. Experimental Cell Research 197, 43–49.
Pócsfalvi, G., Di Landa, G., Ferranti, P., Ritieni, A., Randazzo, G. & Malorni, A. 1997 Observation of non-covalent interactions between beauvericin and oligonucleotides using electrospray ionization mass spectrometry. Rapid Communications in Mass Spectrometry 11, 265–272.
Thakur, R.A. & Smith, J.S. 1997 Liquid chromatography/thermospray/mass spectrometry analysis of beauvericin. Journal of Agricultural and Food Chemistry 45, 1234–1239.
Vey, A., Quiot, J.M. & Vago, C. 1973 Mise en évidence et étude de l'action d'une mycotoxine, la beauvericine, sur des cellules d'insectes cultivées in vitro. Comptes Rendus de l'Académie des Sciences (Paris), Série D 276, 2489–2492.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Castlebury, L., Sutherland, J., Tanner, L. et al. Use of a bioassay to evaluate the toxicity of beauvericin to bacteria. World Journal of Microbiology and Biotechnology 15, 119–121 (1999). https://doi.org/10.1023/A:1008895421989
Issue Date:
DOI: https://doi.org/10.1023/A:1008895421989