Abstract
Two types of complexes were obtained when quercetin (L) was reacted with metal ions in EtOH. The compounds [M(L)Cl2(H2O)2] (M = MnII or CoII) and the semi-oxidized complexes [M(L)2CL2] · 2H2O (M = CdII or HgII) were characterized by elemental analysis., conductivity and magnetic susceptibility measurements, i.r., u.v.–vis. and e.p.r. spectroscopy. The ν(C=O) stretching mode located on the C ring of the ligand and the complexes remains in the same range, showing that this oxygen atom does not participate in coordination to the metal ions. Magnetic susceptibilities and e.p.r. spectra of powdered samples indicated that the monomeric form of the complexes in the solid state, and the paramagnetic nature of the CdII and HgII complexes is attributable to the semiquinone character of the ligand. The antibacterial activity of the metal complexes were tested against five bacterial strains and compared with penicillin activity.
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References
W. Bors and M. Saran, Free Radic. Res. Commun., 2, 289 (1987).
A Negre-Salvayre and R. Salvayre, Free Radic. Biol. Med., 12, 101 (1992).
S. Husain, J. Cillard and P. Cillard, Phytochem., 26, 2489 (1987).
J. Robak and R. Gryglewski, Biochem. Pharmacol., 37, 837 (1988).
I. Afanasev, A. Dorozhko, A. Brodskii, V. Kostyuk and A. Potapovitch, Biochem. Pharmacol., 38, 1763 (1989).
I. Morel, G. Lescout, P. Cogrel, O. Sergent, N. Posdeloup, P. Brissot, P. Cillard and J. Cillard, Biochem. Pharmacol., 45, 13 (1993).
C.G. Pierpont and R.M. Buchanan, Coord. Chem. Rev., 38, 45 (1981).
N.G. Connelly, I. Manners, J.R.C. Protheroe and M.W. Whiteley, J. Chem. Soc., Dalton Trans., 2713 (1984).
A.L. Balch, J. Am. Chem. Soc., 95, 2723 (1973).
A.Y. Girgis, Y.S. Sohn and A.L. Balch, Inorg. Chem., 14, 2327 (1975).
D. Liu and K. Kwasniewska, Bull. Environm. Contam. Toxicol., 27, 289 (1981).
D.D. Perrin, W.L.F. Armergo and D.R. Perrin, Purification of Laboratory Chemicals, Pergamon, New York, 1966.
W.J. Geary, Coord. Chem. Rev., 7, 82 (1971).
C.A. Tsipis, M.P. Sigalas, V.P. Papageorgiou and M.N. Bakola-Christianopoulou, Can. J. Chem., 61, 1500 (1983).
K. Nakamoto, Infrared Spectra of Inorganic and Coordination Compounds, Wiley Interscience, New York, 1970.
P. Pascal, Compt. Rend., 57, 218 (1944).
B.A. Goodman and J.B. Raynor, Adv. Inorg. Chem. and Radiochem., 13, 135 (1970).
R.L. Carlin, Transition Met. Chem., Marcel Dekker, New York, 1965, Vol. I.
J.R. Anacona, E.R. Bastardo and J. Camus, Main Group Met. Chem., 22, 243 (1999).
J.R. Anacona and A. Moreno, Main Group Met. Chem., 22, 573 (1999).
R.P. Burns and C.A. McAuliffe, Adv. Inorg. Chem. and Radiochem., 22, 303 (1979).
H.B. Gray, R. Williams, I. Bernal and E. Billig, J. Am. Chem. Soc., 84, 3596 (1962).
A.B.P. Lever, Inorganic Electronic Spectroscopy, Elsevier, Amsterdam, 1984.
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Bravo, A., Anacona, J.R. Metal complexes of the flavonoid quercetin: antibacterial properties. Transition Metal Chemistry 26, 20–23 (2001). https://doi.org/10.1023/A:1007128325639
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DOI: https://doi.org/10.1023/A:1007128325639