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A longitudinal study of the neuropsychiatric consequences of HIV-1 infection in gay men. II Psychological and health status at baseline and at 12-month follow-up

Published online by Cambridge University Press:  09 July 2009

K. Pugh ,
M. Riccio ,
D. Jadresic ,
A. P. Burgess ,
T. Baldeweg ,
J. Catalan ,
E. Lovett ,
D. A. Hawkins ,
J. Gruzelier  and
C. Thompson
K. Pugh*
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
M. Riccio
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
D. Jadresic
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
A. P. Burgess
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
T. Baldeweg
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
J. Catalan
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
E. Lovett
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
D. A. Hawkins
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
J. Gruzelier
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
C. Thompson
Affiliation:
Academic Department of Psychiatry, Charing Cross and Westminster Medical School, Mental Health Centre, Chelsea and Westminster Hospital, Department of Genito-Urinary Medicine, St Stephen's Clinic, London; Department of Psychiatry, Royal South Hants Hospital, Southampton
*
1Address for correspondence: Dr K. Pugh, Academic Department of Psychiatry Charing Cross and Westminster Medical School, Mental Health Centre. Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9TH
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Synopsis

The aim of this study was to determine whether HIV infection is associated with increased psychosocial distress in the asymptomatic and early symptomatic stages of disease and to determine the factors associated with reporting health symptoms. Subjects included 61 gay men (41 HIV −, 20 HIV +) who were assessed at the time of requesting their first HIV test and again 12 months later. Measures included a detailed standardized psychiatric interview (Present State Examination, PSE), a range of psychosocial self-report measures and a physical symptom checklist. There were no differences between the HIV + and HIV − groups in terms of self-reported symptoms. Multiple regression analysis showed that the symptom reporting was not associated with clinical or immunological markers of disease progression but was associated with measures of psychosocial distress. Although both groups showed elevated levels of psychosocial distress at the time of HIV testing, there were no differences between serostatus groups at follow-up. Multiple regression analysis indicated that the best predictors of PSE scores at follow-up were baseline PSE score and a history of psychiatric illness. Early HIV disease is not associated with increased psychosocial distress and symptom reporting is more closely related to psychological measures than to clinical or immunological markers of disease.

Type
Original Articles
Information
Psychological Medicine , Volume 24 , Issue 4 , November 1994 , pp. 897 - 904
Copyright
Copyright © Cambridge University Press 1994

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