Hostname: page-component-848d4c4894-wg55d Total loading time: 0 Render date: 2024-05-08T23:23:08.709Z Has data issue: false hasContentIssue false
  • English
  • Français

Reversible hyposmia caused by intracranial tumour

Published online by Cambridge University Press:  29 June 2007

Tadashi Ishimaru ,
Takaki Miwa ,
Motohiro Nomura ,
Masayuki Iwato  and
Mrrusuru Furukawa
Tadashi Ishimaru*
Affiliation:
Department of OtorhinolaryngologySchool of Medicine, Kanazawa University, Japan.
Takaki Miwa
Affiliation:
Department of OtorhinolaryngologySchool of Medicine, Kanazawa University, Japan.
Motohiro Nomura
Affiliation:
Department of Neurosurgery, School of Medicine, Kanazawa University, Japan.
Masayuki Iwato
Affiliation:
Department of Neurosurgery, School of Medicine, Kanazawa University, Japan.
Mrrusuru Furukawa
Affiliation:
Department of OtorhinolaryngologySchool of Medicine, Kanazawa University, Japan.
*
Address for correspondence: Tadashi Ishimaru, Department of Otorhinolaryngology, School of Medicine, Kanazawa University, 13–1, Takara-machi, Kanazawa, 920–8641Japan. Fax: +81 76 234 4265 e-mail: ishimar@orl.m.kanazawa.u.ac.jp
Get access Rights & Permissions [Opens in a new window]

Abstract

Two patients with hyposmia caused by an intracranial tumour recovered olfactory functions after craniotomy. The first case was a 68-year-old male with a tumour metastasized from the lung to the right frontal lobe. The second case was a 75-year-old male with meningioma of the right frontal lobe. Results of T & T olfactometry and venous olfaction tests also indicated suspected central hyposmia. Magnetic resonance imaging (MRI) indicated compression of the frontal lobe by intracranial tumour. Pressure on the olfactory centre located in the frontal lobe produced hyposmia. Decompression of the frontal lobe by craniotomy improved the sense of smell. Therefore, some cases of olfactory disturbance caused by intracranial tumour may be reversible if they are the result of simple compression of the olfactory centre.

Keywords

SmellOlfactory pathwaysBrain neoplasms
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 113 , Issue 8 , August 1999 , pp. 750 - 753
Copyright
Copyright © JLO (1984) Limited 1999

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Furukawa, M., Kamide, M., Miwa, T., Umeda, R. (1988) Significance of intravenous olfaction test using thiamine propyldisulfide (Alinamin) in olfactometry. Auris Nasus Larynx 15: 25–31.CrossRefGoogle ScholarPubMed
Iida, Y., Naito, M., Asahina, N., Okuda, K., Kato, M., Okamoto, Y., Zusho, H., Tanioka, H. (1994) Magnetic resonance imaging of the olfactory apparatus. Archives of Otolaryngology – Head and Neck Surgery 120: 869–872.CrossRefGoogle ScholarPubMed
Kimura, Y., Donjo, T., Tsukatani, T., Sakumoto, M., Miwa, T., Furukawa, M. (1993) Clinical observation on central olfactory disorders. Oto-Rhino-Laryngology (Tokyo) 36: 709–716.Google Scholar
Koizuka, I., Yano, H., Nagahara, M., Mochizuki, R., Seo, R., Shimada, K., Kubo, T., Nogawa, T. (1994) Functional imaging of the human olfactory cortex by magnetic resonance imaging. ORL 56: 273–275.CrossRefGoogle ScholarPubMed
Morita, M. (1987) Dissociation phenomenon occurring between olfactory detection threshold and recognition threshold and its clinical significance. Nippon Jibiinkoka Gakkai Kaiho 90: 1856–1863.CrossRefGoogle ScholarPubMed
Takagi, S. F. (1980) Dual nervous system for olfactory functions in the mammals. In Olfaction and Taste VII, Information Retrieval, London and Washington, pp 275–278.Google Scholar
Takagi, S. F. (1989) Human Olfaction. University of Tokyo Press, Tokyo, pp 35–69.Google Scholar
Takeuchi, H., Kubota, T., Kabuto, M., Izaki, K. (1993) Ruptured suprasellar dermoid cyst presenting olfactory delusion (Eigengeruchs erlebnis). Neurosurgery 33: 97–99.Google ScholarPubMed
Zatorre, R. J., Jones-Gotman, M., Evance, A. C., Meyer, E. (1992) Functional localization and lateralization of human olfactory cortex. Nature 360: 339–340.CrossRefGoogle ScholarPubMed