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Laryngeal malakoplakia

Published online by Cambridge University Press:  29 June 2007

A. K. Gupta
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012
S. B. S. Mann*
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012
K. B. Singh
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012
K. Joshi
Affiliation:
Department of Pathology, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012.
S. Sajeeda
Affiliation:
Department of Otolaryngology, Head and Neck Surgery, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012
Nandita Kakkar
Affiliation:
Department of Pathology, Postgraduate Institute for Medical Education and Research, Chandigarh - 160 012.
*
Address for correspondence: Prof. S. B. S. Mann, Professor and Head, Department of ENT, PGIMER, Chandigarh - 160 012India.

Abstract

We report a case of malakoplakia of the epiglottis in a 45-year-old female patient. Only three cases of laryngeal malakoplakia have been reported in the world literature, one of which was associated with tracheal malakoplakia. To our knowledge this is the first reported case of isolated malakoplakia of the epiglottis. Malakoplakia, a rare granulomatous lesion, has been seen more frequently in the urinary tract. Other organs like the genito-urinary tract, testis, epididymis, lymph nodes, middle ear, nasopharynx, tonsil and retroperitoneal tissue have been also involved though less frequently.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1997

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References

Abdou, N. I., Pombejara, C. N., Sagawa, A. (1977) Malakoplakia: evidence for monocyte lysosomal abnormality correctable by cholinergic agonist in vitro and in vivo. New England Journal of Medicine 297: 14131419.CrossRefGoogle ScholarPubMed
Benizri, E., Hofman, P., Chevallier, D., Fabiani, P., Suhler, A., Peyrottes, A., de Graeve, B., Marie, J. F., Volpe, P., Amiel, J. (1993) Urinary malacoplakia. Anatomoclinical analysis of three cases with long-term follow-up. Journal d'Urologie 99(1): 3843.Google Scholar
Cozar Olmo, J. M., Carcamo, P., Gaston ‘de Iriarte’, E., Jimenez, F., Martinez-Pineiro, L., Martinez-Pineiro, J. A. (1993) Genitourinary malakoplakia. British Journal of Urology 72(1): 612.CrossRefGoogle ScholarPubMed
Flint, A., Mured, T. M. (1984) Malakoplakia and malakoplakia-like lesions of the upper gastrointestinal tract. Ultra- structural Pathology 7: 167.CrossRefGoogle Scholar
Long, J. P., Althausen, A. F. (1989) Malacoplakia: a 25-year experience with a review of the literature. Journal of Urology 141: 13281331.CrossRefGoogle ScholarPubMed
Lou, T. Y., Teplitz, C. (1974) Malakoplakia: pathogenesis and ultrastructural morphogenesis. Human Pathology 5: 191207.CrossRefGoogle ScholarPubMed
Michaelis, L., Gutmann, C. (1902) Uber Einschlusse in Blasentumoren. Journal of Clinical Medicine 47: 208215.Google Scholar
Mollo, J., Groussard, O., Baldeyrou, P., Molas, G., Fournier, M., Pariente, R. (1994) Tracheal malacoplakia. Chest 105: 608610.CrossRefGoogle ScholarPubMed
Oliver, J. M. (1976) Impaired microtubule function correctable by cyclic GMP and cholingeric agonist in the Chedial Higashi syndrome. American Journal of Pathology 85: 395.Google Scholar
Saleem, M. A., Milford, D. V., Raafat, F., White, R. H. R. (1993) Renal parenchymal malakoplakia: a case report and review of the literature. Pediatric Nephrology 7: 256258.CrossRefGoogle ScholarPubMed
Stanton, M. J., Maxted, W. (1981) Malakoplakia: a study of the literature and current concepts of pathogenesis, diagnosis and treatment. Journal of Urology 125: 139146.CrossRefGoogle ScholarPubMed
Streem, B. S. B. (1984) Genitourinary malacoplakia in renal transplant recipients: pathogenic, prognostic and therapeutic considerations. Journal of Urology 132: 1012.CrossRefGoogle ScholarPubMed
Van Furth, R., van't Wout, J. W., Wertheimer, P. A., Zwartendijk, J. (1992) Ciprofloxacin for treatment of malakoplakia. Lancet 339: 148149.CrossRefGoogle ScholarPubMed
Witherington, R., Branan, W. J., Wray, B. B., Best, G. K. (1984) Malakoplakia associated with vesicoureteral reflux and selective immunoglobulin A deficiency. Journal of Urology 132: 975977.CrossRefGoogle ScholarPubMed