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Hearing impairment and facial palsy as initial signs of Wegener's granulomatosis

Published online by Cambridge University Press:  29 June 2007

I. H. Calonius  and
C. K. Christensen
I. H. Calonius
Affiliation:
Department of Gynaecology and Obstetrics, Silkeborg Centralsygehus, 8600 Silkeborg, Denmark.
C. K. Christensen
Affiliation:
Department of Otorhinolaryngology, University Hospital, Aarhus, Denmark.
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Summary

In two patients with Wegener's granulomatosis, treatment-resistant serous otitis media was followed by unilateral facial nerve palsy. Later both patients developed uraemia due to extracapillary glomerulonephritis. In one of them, who was treated with prednisone and cyclophosphamide, renal function improved, while in the other patient it remained impaired. Both patients suffered lasting hearing impairment in spite of general improvement during the course of the disease. The facial nerve palsy improved slightly in one, while no improvement was seen in the other.

The possibility of Wegener's granulomatosis or other autoimmune collagen diseases should be considered in cases of treatment-resistant serous otitis media. Early diagnosis and treatment can possibly save the patient from the lifethreatening consequences of these diseases.

Type
Clinical records
Information
The Journal of Laryngology & Otology , Volume 94 , Issue 6 , June 1980 , pp. 649 - 657
Copyright
Copyright © JLO (1984) Limited 1980

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References

REFERENCES

Anderson, J. M., Jamieson, D. G., and Jefferson, J. M. (1975) Quarterly Journal of Medicine, 44, 309.Google Scholar
Atkins, J. P., and Eisman, S. H., (1959) Annals of Otology, Rhinology and Laryngology, 68, 524.CrossRefGoogle Scholar
Blatt, J. M., Holbrooke, S. S., Rubin, P., Furstenberg, A. C., Maxwell, J. H., and Schull, W. J. (1959) Archives of Otolaryngology, 70, 707.CrossRefGoogle Scholar
Blatt, J. M., and Lawrence, M. (1961) Archives of Otolaryngology, 73, 639.CrossRefGoogle Scholar
Brown, H. A., and Woolner, L. B. (1960) Annals of Otology, Rhinology and Laryngology, 69, 810.CrossRefGoogle Scholar
Cody, D. T. R., and Sones, D. A. (1971) The Laryngoscope, 81, 1208.CrossRefGoogle Scholar
Deremee, R. A., McDonald, T. J., Harrison, E. G., and Coles, D. T. (1976) Mayo Clinic Proceedings, 51, 777.Google Scholar
Dolan, D. L., Lemmon, G. B., Tettelbaum, S. L. (1966) American Journal of Medicine, 41, 285.CrossRefGoogle Scholar
Dudley, J. P., and Goodman, M. (1969) Archives of Otolaryngology, 90, 139.CrossRefGoogle Scholar
Fauci, A. S., Balow, J. E., and Wolff, S. M. (1975) Proceedings of the 6th International Congress of Nephrology, Florence (1976), Karger, Basel, 486–491.Google Scholar
Herberts, G., Hillerdal, O., and Ranström, S. (1957) Acta Otolaryngologica, 48, 205.CrossRefGoogle Scholar
Jensen, H., Ølgaard, K., and Faarup, P. (1974) Acta Medica Scandinavica, 196, 383.CrossRefGoogle Scholar
Jepsen, O., Calonius, I. H., and Søgaard, H. (1978) Broncho-Pneumologie, 82, 1594.Google Scholar
Kremer, D., Hood, W. G., and Nuki, G. (1975) British Journal of Clinical Practice, 29, 347.Google Scholar
McGovern, J. H., Koningsmark, B. W., and Sydnor, J. B. (1972) The Laryngoscope, 82, 1594.CrossRefGoogle Scholar
Olsen, S., and Petersen, V. P. (1975) Acta Medica Scandinavica, 198, 145.CrossRefGoogle Scholar
Peitersen, E., and Carlsen, B. H. (1966) Acta Otolaryngologica, 61, 189.CrossRefGoogle Scholar
Per-Lee, J. H., and Parsons, R. C. (1969) Southern Medical Journal, 62, 161.CrossRefGoogle Scholar
Powers, W. H. (1974) Otolaryngologic Clinics of North America, 7, 397.CrossRefGoogle Scholar
Reza, M. J., Dornfeld, L., Goldberg, L. S., Bluestone, R., and Pearsons, C. M. (1975) Arthritis and Rheumatism, 18, 501.CrossRefGoogle Scholar
Rose, G. A., and Spencer, H. (1957) Quarterly Journal of Medicine, 26, 43.Google Scholar
Sack, M., Cassidy, J. T., and Bole, G. G. (1975) Journal of Rheumatology, 2, 411.Google Scholar
Sergent, J. S., and Christian, C. L. (1974) Annals of International Medicine, 81, 195.CrossRefGoogle Scholar
Tuma, S., Chaimovitz, C., Szylman, P., Gellei, B., and Better, O. S. (1976) Journal of the American Medical Association, 235, 280.CrossRefGoogle Scholar