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Comprehensive management of type A acute aortic dissection in the paediatric population with ACTA 2 mutation: case reports and literature review of paediatric aortic dissection

Published online by Cambridge University Press:  04 May 2023

Fumiya Yoneyama Open the ORCID record for Fumiya Yoneyama [Opens in a new window] ,
Ziyad Binsalamah  and
Jeffery S. Heinle
Fumiya Yoneyama*
Affiliation:
Division of Congenital Heart Surgery, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, USA
Ziyad Binsalamah
Affiliation:
Division of Congenital Heart Surgery, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, USA
Jeffery S. Heinle
Affiliation:
Division of Congenital Heart Surgery, Texas Children’s Hospital, Baylor College of Medicine, Houston, Texas, USA
*
Address for correspondence: Dr F. Yoneyama, MD, PhD, Division of Pediatric Cardiovascular Surgery, Texas Children Hospital, 6651 Main St, Houston, TX 77030, USA. Tel: 832-824-1000; Fax: 832-825-1904. E-mail: fxyoneya@texaschildrens.org
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Abstract

Acute aortic dissection in the paediatric population is rare but lethal. We present two paediatric cases of type A acute aortic dissection that required emergent procedures and were later found to have genetic mutations. High index of suspicion, early clinical diagnosis, prompt treatment, the advantageous collaboration between the paediatric team and aortic surgeons, and familial genetic testing are paramount to achieve a good outcome.

Keywords

Paediatric aortic dissectiongenetic mutationsaortic surgery
Type
Brief Report
Information
Cardiology in the Young , Volume 33 , Issue 11 , November 2023 , pp. 2369 - 2374
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Copyright
© The Author(s), 2023. Published by Cambridge University Press

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