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Left ventricular–right ventricular interaction in paediatric idiopathic dilated cardiomyopathy

Published online by Cambridge University Press:  08 February 2013

Martin Koestenberger*
Affiliation:
Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Graz, Austria
William Ravekes
Affiliation:
Division of Pediatric Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
*
Correspondence to: Dr M. Koestenberger, PhD, MD, Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Auenbruggerplatz 34/2, A-8036 Graz, Austria. Tel: ++43 316 385 84276; Fax: ++43 316 385 13682; E-mail: Martin.Koestenberger@medunigraz.at or koestenbergerm@gmx.at
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Abstract

Type
Letter to the Editor
Copyright
Copyright © Cambridge University Press 2013 

To the Editor,

We read with interest the article “The role of right ventricular function in paediatric idiopathic dilated cardiomyopathy” from Groner et al.Reference Groner, Yau and Lytrivi 1 In our opinion, this is a very interesting manuscript describing right ventricular systolic and diastolic dysfunction in children who suffer from idiopathic dilated cardiomyopathy. The authors state that there is also a need for detailed evaluation of the right ventricular function parameters, for example the tricuspid annular plane systolic excursion and the tricuspid annular peak systolic velocity, among these children.Reference Groner, Yau and Lytrivi 1 They found that the tricuspid annular plane systolic excursion and the tricuspid annular peak systolic velocity were significantly lower in these patients than in the control group as a possible sign of relevant left ventricular–right ventricular interaction. Given the known left ventricular–right ventricular interaction in patients with tetralogy of FallotReference Kempny, Diller and Orwat 2 or dilated cardiomyopathy,Reference Osculati, Malfatto, Chianca and Perego 3 we support the notion of Groner et alReference Groner, Yau and Lytrivi 1 that right ventricular dysfunction is under-recognised in children with dilated cardiomyopathy. To be able to fully assess changes in systolic right ventricular function in patients with congenital heart defects, sufficient reference data of normal patients are required. For the convenience of the audience of Cardiology in the Young and especially for centres performing detailed echocardiographic investigations of the right ventricle, we want to add that our group has published normal tricuspid annular peak systolic velocity values with z-scores for healthy children.Reference Koestenberger, Nagel and Ravekes 4 In our opinion, the available z-scores will enable physicians to compare every single measured tricuspid annular plane systolic excursion and tricuspid annular peak systolic velocity value of patients with dilated cardiomyopathy to age-related normal z-score values. It would further be of interest to investigate the time point at which the decreased tricuspid annular plane systolic excursion and/or tricuspid annular peak systolic velocity values in patients with dilated cardiomyopathy will fall below the – 2 standard deviation, and whether values below – 2 standard deviation will correlate well with clinical worsening of these patients. We want to thank the authors for addressing the need for a careful and systematic evaluation of the right ventricle among children suffering from idiopathic dilated cardiomyopathy.Reference Groner, Yau and Lytrivi 1 In our opinion, the right ventricular function should be carefully investigated in children and in adult patients with dilated cardiomyopathy with over time potentially decreased systolic right ventricular function.

References

1. Groner, A, Yau, J, Lytrivi, ID, et al. The role of right ventricular function in pediatric idiopathic dilated cardiomyopathy. Cardiol Young, 2012; 1–7 [Epub ahead of print]. http://dx.doi.org/10.1017/S104795111200114X.Google Scholar
2. Kempny, A, Diller, GP, Orwat, S, et al. Right ventricular–left ventricular interaction in adults with tetralogy of Fallot: a combined cardiac magnetic resonance and echocardiographic speckle tracking study. Int J Cardiol 2012; 154: 259264.CrossRefGoogle ScholarPubMed
3. Osculati, G, Malfatto, G, Chianca, R, Perego, G. Left-to-right systolic ventricular interaction in patients undergoing biventricular stimulation for dilated cardiomyopathy. J Appl Physiol 2010; 109: 418423.CrossRefGoogle ScholarPubMed
4. Koestenberger, M, Nagel, B, Ravekes, W, et al. Reference values of tricuspid annular peak systolic velocity in healthy pediatric patients, calculation of Z score, and comparison to tricuspid annular plane systolic excursion. Am J Cardiol 2012; 109: 116121.Google Scholar