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Quantification of collateral aortopulmonary flow in patients subsequent to construction of bidirectional cavopulmonary shunts

Published online by Cambridge University Press:  18 July 2008

Ryo Inuzuka ,
Hiroyuki Aotsuka ,
Hiromichi Nakajima ,
Hirokuni Yamazawa ,
Kenji Sugamoto ,
Shunsuke Tatebe ,
Mitsuru Aoki  and
Tadashi Fujiwara
Ryo Inuzuka*
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Hiroyuki Aotsuka
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Hiromichi Nakajima
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Hirokuni Yamazawa
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Kenji Sugamoto
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Shunsuke Tatebe
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Mitsuru Aoki
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
Tadashi Fujiwara
Affiliation:
The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, Chiba, Japan
*
Correspondence to: Ryo Inuzuka, MD, The Departments of Pediatric Cardiology and Pediatric Cardiothoracic Surgery, Chiba Children’s Hospital, 579-1 Heta-cho, Midori-ku, Chiba-city, Chiba, Japan. Tel: +81 43 292 2111; Fax: +81 43 292 3815; E-mail: inuzukar-tky@umin.ac.jp
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Abstract

Objectives

We sought to provide a new method for quantifying collateral aortopulmonary flow in patients subsequent to construction of a bidirectional cavopulmonary shunt, and to clarify the clinical advantages of the new method.

Methods

We performed lung perfusion scintigraphy and cardiac catheterization in 10 patients subsequent to construction of a bidirectional cavopulmonary shunt. First, the ratio of collateral to systemic flow was determined by whole-body images of lung perfusion scintigraphy, dividing the total lung count by the total body count minus the total lung count. Second, we integrated lung perfusion scintigraphy and cardiac catheterization data using a formula derived from the Fick principle, taking the ratio of pulmonary to systemic flow to be 1 plus the ratio calculated above and multiplied by the systemic saturation minus the inferior caval venous saturation divided by the pulmonary venous saturation minus the inferior caval venous saturation. Finally, the amount of collateral flow was obtained from the ratio of pulmonary to systemic flow. We evaluated the impact of collateral flow on the calculation of pulmonary vascular resistance.

Results

The median age at bidirectional cavopulmonary shunt was 1.41 years, and the median age at catheterization was 2.33 years. The mean amount of collateral flow was 1.75 ± 0.46 litres/min/m2. The pulmonary vascular resistance calculated without considering the collateral flow was overestimated by an average of 57 ± 23%, compared to the resistance calculated with our new method.

Conclusions

The use of scintigraphy combined with catheterization allows accurate determination of aortopulmonary collateral flow, and avoids overestimation of pulmonary vascular resistance in these candidates for the Fontan circulation.

Keywords

Cardiac catheterizationlung perfusion scintigraphybidirectional Glenn procedure
Type
Original Article
Information
Cardiology in the Young , Volume 18 , Issue 5 , October 2008 , pp. 485 - 493
Copyright
Copyright © Cambridge University Press 2008

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