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Interactions between chemotherapy and immunity in bovine theileriosis

Published online by Cambridge University Press:  06 April 2009

F. E. G. Cox
F. E. G. Cox
Affiliation:
Division of Life Sciences, King's College London, Campden Hill Road, London W8 7AH
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Summary

In bovine theileriosis the use of chemotherapy to control an infection sufficiently long to permit the establishment of a solid protective immune response has been developed as a routine vaccination procedure. Infections with Theileria parva and T. annulata can be prevented by the administration of carefully controlled numbers of sporozoites simultaneously with a long acting tetracycline and this form of immunization has been widely used for the control of East Coast fever in Africa with considerable success. In this review, the nature of the chemotherapy, the immune response and the interactions between chemotherapy and immunity in the development of infection-and-treatment immunization procedures are discussed.

Keywords

Theileria parvaTheileria annulataEast Coast feverchemoimmunoprophylaxis
Type
Research Article
Information
Parasitology , Volume 105 , Issue S1: Chemotherapy and the immune system , January 1992 , pp. S79 - S84
Copyright
Copyright © Cambridge University Press 1992

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