Hostname: page-component-848d4c4894-pftt2 Total loading time: 0 Render date: 2024-05-01T11:31:38.595Z Has data issue: false hasContentIssue false
  • English
  • Français

S-100 protein and myoepithelial neoplasms

Published online by Cambridge University Press:  29 June 2007

J. G. Batsakis ,
N. G. Ordonez ,
J. Ro ,
J. M. Meis  and
J. M. Bruner
J. G. Batsakis*
Affiliation:
Department of Pathology, University of Texas System Cancer centre, M. D. Anderson Hospital, Houston, Texas 77030.
N. G. Ordonez
Affiliation:
Department of Pathology, University of Texas System Cancer centre, M. D. Anderson Hospital, Houston, Texas 77030.
J. Ro
Affiliation:
Department of Pathology, University of Texas System Cancer centre, M. D. Anderson Hospital, Houston, Texas 77030.
J. M. Meis
Affiliation:
Department of Pathology, University of Texas System Cancer centre, M. D. Anderson Hospital, Houston, Texas 77030.
J. M. Bruner
Affiliation:
Department of Pathology, University of Texas System Cancer centre, M. D. Anderson Hospital, Houston, Texas 77030.
*
John G. Batsakis, M. D., Department of Pathology, M. D. Anderson Hospital, Houston, Texas 77030, U.S.A.
Get access Rights & Permissions [Opens in a new window]

Abstract

Besides advancing our knowledge of histogenesis, immuno-cytochemical studies of salivery gland tumors have added an important objective component to the diagnosis and classification of the tumors. Cellular localization of S-100 protein now allows identification of myoepithelial cells and tumors composed of these cells. The four tumors presented in this report illustrate the diagnostic advantages afforded by S-100 protein immunocytochemistry.

Type
Research Article
Information
The Journal of Laryngology & Otology , Volume 100 , Issue 6 , June 1986 , pp. 687 - 698
Copyright
Copyright © JLO (1984) Limited 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Barnes, L., Appel, B. N., Perez, H. and El-Attar, A. M. (1985) Myoepitheliomas of the head and neck: case report and review. Journal of Surgical Onocology, 28: 21–28.CrossRefGoogle ScholarPubMed
Batsakis, J. G. (1980) Salivary gland neoplasia: an outcome of modified morphogensis and cytodifferentiation. Oral Surgery, Oral Medicine, Oral Pathology, 49: 229–232.CrossRefGoogle Scholar
Batsakis, J. G., Kraemer, B. B. and Sciubba, J. J. (1983). The pathology of head and neck tumors: the myoepithelial cell and its participation in salivary gland neoplasia. Part 17. Head and Neck Surgery, 5: 222–233.CrossRefGoogle ScholarPubMed
Corio, R. L., Sciubba, J. J., Brannon, R. B. and Batsakis, J. G. (1982) Epithelial-myoepithelial carcinoma of intercalated duct origin. Oral Surgery, Oral Medicine, Oral Pathology, 53: 280–287.CrossRefGoogle ScholarPubMed
Erlandson, R. A., Cardon-Cardo, C. and Higgins, P. J. (1984) Histogenesis of benign pleomorphic adenoma (mixed tumor) of the major salivary glands. An ultrastructural and immunohistochemical study. American Journal of Surgical Pathology, 8: 803–820.CrossRefGoogle ScholarPubMed
Hara, K., Ito, M., Takeuchi, J., Iijima, S., Endo, T. and Hidaka, H. (1983) Distribution of S-100 protein in normal salivary glands and salivary gland tumors. Virchows Archives, A. Pathological Anatomy, 401: 237–249.CrossRefGoogle ScholarPubMed
Hsu, S-M., Raine, L. and Fanger, H. (1981) case of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody peroxidase (PAP). Journal of Histochemistry and Cytochemistry, 29: 577–580.CrossRefGoogle Scholar
Kahn, H. J., Marks, A., Thom, H. and Baumal, R. (1983) Role of antibody to S-100 protein in diagnostic pathology. American Journal of Clinical Pathology, 79: 341–347.CrossRefGoogle ScholarPubMed
Kahn, H. J., Baumal, R., Marks, A. and Dardick, I. (1985) Myoepithelial cells in salivary gland tumors. An immunohistochemical study. Archives of Pathology and Laboratory Medicine, 109: 190–195.Google ScholarPubMed
Luna, M. A., Ordonez, N. G., Mackay, B., Batsakis, J. G. and Guillamonui, O. (1985) Salivary epithelial-myoepithelial carcinoma of intercalated ducts: a clinical, electron microscopic and immunohistochemical study. Oral Surgery, Oral Medicine, Oral Pathology. 59: 482–490.CrossRefGoogle Scholar
Nakajima, T., Kameya, T., Watanabe, S., Hirota, T. and Shimosato, Y. (1984) S-100 protein distribution in normal and neoplastic tissues, in Advances in Immunohistochemistry, Editor Dellis, R. A., pp. 141–158, Masson, New York, New York.Google Scholar
Regezi, J. A. and Batsakis, J. G. (1977) Histogenesis of salivary gland neoplasms. Otolaryngologic Clinics of North America, 10: 297–307.CrossRefGoogle ScholarPubMed
Sato, M., Hayshi, Y., Yoshida, H., Yangagawa, T., Yura, Y. and Nitta, T. (1984). Search for specific markers of neoplastic epithelial duct and myoepithelial cell lines established from human salivary gland and characterization of their growth in-vitro. Cancer, 54: 2959–2967, 1984.3.0.CO;2-5>CrossRefGoogle ScholarPubMed