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The proportional frequency of the human and bovine types of tubercle bacilli in human pulmonary tuberculosis in the middle and south of Scotland

Published online by Cambridge University Press:  15 May 2009

A. Stanley Griffith
A. Stanley Griffith
Affiliation:
From the Field Laboratories, Cambridge
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1. The types of tubercle bacilli have been determined in the sputum of 515 cases of pulmonary tuberculosis occurring in the middle and south of Scotland.

2. Of the 515 cases 484 were human (476 eugonic and eight dysgonic) and thirty-one were bovine infections.

3. With the exception of the strains from one case (case 28) all the bovine strains, seventy in number, were typical culturally and fully virulent for rabbits.

4. The attenuated strains, two in number, from case 28 were slightly less virulent than typical bovine strains for rabbits and (one strain) for guinea-pigs.

5. The percentage of bovine infections found in this series, including the Cumberland case, during the years 1931–9 was 6·0, but excluding that case it was 5·8.

6. The percentage of bovine infections found by Munro during about the same period and covering the same regions was 5·0%.

7. In Munro's series strains of bovine tubercle bacilli were obtained from fifty-eight out of 1165 persons (5·0%). Five of his cases yielded attenuated bovine strains and in one of these the pulmonary tuberculosis was preceded by tuberculosis of the thoracic spine.

8. In my series the attenuated tubercle bacilli came from a case (case 28) of pulmonary tuberculosis which was preceded nearly 20 years previously by tuberculosis of the lower dorsal spine.

Dr Munro and others have made post-mortem examinations on cases of phthisis pulmonalis due to bovine bacilli, but I wish to defer reference to these until we can review them altogether.

In this series there are seven instances of cervical gland enlargement and one instance (case 28) of spinal tuberculosis occurring previous to the development of phthisis pulmonalis. These, I think, are examples of alimentary infection with the bovine tubercle bacillus. Thus, with the three autopsies previously mentioned, there are eleven cases, or about one-third, which are almost certainly alimentary in origin. As for the rest of the cases, 20 in number, no glandular enlargements in neck or abdomen were detected but the majority, if not all, were probably alimentary in origin, since all the persons drank a lot of raw milk and only five came into direct contact with cattle in their employment.

Type
Research Article
Information
Journal of Hygiene , Volume 40 , Issue 3 , May 1940 , pp. 365 - 376
Copyright
Copyright © Cambridge University Press 1940

References

REFERENCES

Cobbett, L. (1907). The relations of human and animal tuberculosis. Roy. Comm. on Tuberc. App. 2nd Int. Rep.Google Scholar
Griffith, A. S. (1911). The relations of human and animal tuberculosis. Roy. Comm. on Tuberc. App. Fin. Rep. 1.Google Scholar
Griffith, A. S. (1914). Further investigations of the types of tubercle bacilli occurring in the sputum of phthisical persons. Brit. med. J. 1, 1171.CrossRefGoogle Scholar
Griffith, A. S. & Munro, W. T. (1933). Phthisis pulmonalis due to the bovine type of tubercle bacillus. Lancet, 1, 399.CrossRefGoogle Scholar
Griffith, A. S. & Munro, W. T. (1935). Family tuberculosis due to bovine tubercle bacilli. Brit. med. J. 2, 147.CrossRefGoogle ScholarPubMed
Griffith, A. S. & Smith, J. (1938). Bovine phthisis, its incidence in north-east Scotland. Lancet, 1, 739.CrossRefGoogle Scholar
Koch, R. (1908). The Relation of Human and Bovine Tuberculosis. International Congress on Tuberculosis, Washington.CrossRefGoogle Scholar
Leighton, G. & McKinlay, P. L. (1934). Milk Consumption in Scotland. Department of Health for Scotland.Google Scholar
Munro, W. T. (1939). Epidemiological aspects of pulmonary tuberculosis due to bovine type tubercle bacilli. Trans. Tuberc. Soc. Scot. 27.Google Scholar
Munro, W. T. (1940). 21st Ann. Rep. Fife and Kinross Joint Sanatorium Board.Google Scholar
Munro, W. T. & Cummlng, W. M. (1926). The virulence of tuberculous viruses. Edin. med. J. 33, 97.Google ScholarPubMed
Wang, C. Y. (1916). Isolation of tubercle bacilli from sputum and determination of their type. J. Path. Bact. 21, 14.CrossRefGoogle Scholar