Hostname: page-component-8448b6f56d-t5pn6 Total loading time: 0 Render date: 2024-04-24T06:20:10.959Z Has data issue: false hasContentIssue false
  • English
  • Français

Statistical model for characterizing epistatic control of triploid endosperm triggered by maternal and offspring QTLs

Published online by Cambridge University Press:  26 September 2005

YUEHUA CUI  and
RONGLING WU
YUEHUA CUI
Affiliation:
Department of Statistics, University of Florida, Gainesville, FL 32611, USA
RONGLING WU
Affiliation:
Department of Statistics, University of Florida, Gainesville, FL 32611, USA
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

To study the effects of maternal and endosperm quantitative trait locus (QTL) interaction on endosperm development, we derive a two-stage hierarchical statistical model within the maximum-likelihood context, implemented with an expectation-maximization algorithm. A model incorporating both maternal and offspring marker information can improve the accuracy and precision of genetic mapping. Extensive simulations under different sampling strategies, heritability levels and gene action modes were performed to investigate the statistical properties of the model. The QTL location and parameters are better estimated when two QTLs are located at different intervals than when they are located at the same interval. Also, the additive effect of the offspring QTLs is better estimated than the additive effect of the maternal QTLs. The implications of our model for agricultural and evolutionary genetic research are discussed.

Type
Research Article
Information
Genetics Research , Volume 86 , Issue 1 , August 2005 , pp. 65 - 75
Copyright
© 2005 Cambridge University Press