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R-Factor elimination by thymine starvation

Published online by Cambridge University Press:  14 April 2009

R. J. Pinney  and
J. T. Smith
R. J. Pinney
Affiliation:
Microbiology Section, Department of Pharmaceutics, The School of Pharmacy, University of London, Brunswick Square, London, WC1N 1AX
J. T. Smith
Affiliation:
Microbiology Section, Department of Pharmaceutics, The School of Pharmacy, University of London, Brunswick Square, London, WC1N 1AX

Summary

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R-factor 1818, which is refractory to curing by acridines or ethidium bromide from Escherichia coli K 12 and Klebsiella aerogenes 418 hosts, was eliminated from thymineless mutants of these organisms under conditions of thymine starvation. Neither R-7268 nor R-TEM could be eliminated by this method. The concurrence of R-TEM with R-1818 inhibited the curing of R-1818, whereas R-7268 had no effect on R-1818 elimination

Type
Research Article
Information
Genetics Research , Volume 18 , Issue 2 , October 1971 , pp. 173 - 177
Copyright
Copyright © Cambridge University Press 1971

References

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