Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-25T04:34:45.260Z Has data issue: false hasContentIssue false
  • English
  • Français

Prediction of duration of psychosis before first admission

Published online by Cambridge University Press:  16 April 2020

H Verdoux ,
C Bergey ,
F Assens ,
F Abalan ,
B Gonzales ,
P Pauillac ,
O Fournet ,
F Liraud ,
JP Beaussier  and
C Gaussares
...Show all authors
H Verdoux
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux Hôpital Charles Perrens, Bordeaux, France
C Bergey
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
F Assens
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
F Abalan
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
B Gonzales
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
P Pauillac
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux Hôpital Charles Perrens, Bordeaux, France
O Fournet
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux Hôpital Charles Perrens, Bordeaux, France
F Liraud
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
JP Beaussier
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
C Gaussares
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
B Etchegaray
Affiliation:
Hôpital Charles Perrens, Bordeaux, France
M Bourgeois
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux Hôpital Charles Perrens, Bordeaux, France
J van Os
Affiliation:
University of Maastricht, The Netherlands
Get access

Summary

Objective:

To assess the factors predicting the delay between onset of psychotic symptoms and first admission in a populationbased sample.

Method:

The duration of psychosis before admission was ascertained in a standardised way for 59 consecutively first-admitted patients presenting with psychotic symptoms.

Results:

The median of the duration of psychosis before admission was 3 months (interquartile range 0.5-14). A delay ≥ 3 months was independently predicted by family history of psychiatric hospitalisation (odds ratio [OR] = 12.1, 95% confidence interval [CI] 1.15-97.0, P = 0.02). low educational level (OR = 7.7, 95% CI 1.0-50.0, P = 0.05), poor global adjustment in the preceding year (OR = 0.93, 95% CI 0.860.99, P = 0.04). and by greater global severity of illness at admission (OR = 4.0, 95% CI 0.87-18.3, P = 0.07).

Conclusion:

As these factors are also known to predict poor outcome, our results suggest that the association between duration of untreated psychosis and poor prognosis may be mediated, at least in part, by such demographic and clinical variables.

Keywords

first admissionpsychosis durationpredictive factorsoutcome
Type
Original article
Information
European Psychiatry , Volume 13 , Issue 7 , November 1998 , pp. 346 - 352
Copyright
Copyright © Elsevier, Paris 1998

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association. DSM-III-R. Diagnostic and Statistical Manual of Mental Disorders 3rd ed, Revised. Washington, DC: APA; 1587Google Scholar
American Psychiatric Association. DSM-IV. Diagnostic and Statistical Manual of Mental Disorders 4th ed, Revised. Washington, DC: APA; 1994Google Scholar
Beiser, MErickson, DFleming, JAEIacono, WCEstablishing the onset of psychotic illness Am J Psychiatry 1993 ; 150 : 1349-54Google ScholarPubMed
Crow, TJMcMillan, JFJohnson, ALJohnstone, ECA randomised controlled trial of prophylactic neuroleptic treatment Br J Psychiatry 1986 ; 148 : 120-7CrossRefGoogle ScholarPubMed
Endicott, JAndreasen, NSpitzer, RLFamily History-Resenrch Diagnostic Criteria (3rd Ed). Biometrics Research New York: New York State Psychiatric institute; 1978Google Scholar
Guota, SAndreasen, NCArdnt, SFlaum, MHubbard, WZiebeli, SThe IOWA longitudinal study of recent onset psychosis; one year follow-up of first episode patients Schizophr Res 1997 ; 23 : 1–13Google Scholar
Guy, WAssessment Manual for Psychopharmacology. National Institute of Mental Health, Early Clinical Drug Evaluation Unit; 1976Google Scholar
Haas, GKSweeney, JAPremorbid and onset features of firstepisode schizophrenia Schizophr Bull 1992 ; 18 : 373-86CrossRefGoogle Scholar
Häher, Han der Heiden, WBehrens, SGattaz, WFHambrecht, MLöffler, W et al. Causes and consequences of the gender differences in age at onset of schizophrenia Schizophr Bull 1998 ; 24 : 99–113Google Scholar
Häfner, HRiechler-Rössler, AHambrecht, MMaurer, KMeissner, SSchmidtke, A et al. IRAOS: an instrument for the assessment of onset and early course of schizophrenia Schizophr Res 1992 ; 6 : 209-23CrossRefGoogle ScholarPubMed
Kay, SRFizbein, AOpler, LAThe positive and Negative Syndrome Scale (PANS.% for schizoohrenia Schizoahr Bull 1987 : 13:261-76CrossRefGoogle Scholar
Kendler, KSTsuang, MTOutcome and familial psychopathology in schizophrenia Arch Gen Psychiatry 1988 ; 45 : 338-46CrossRefGoogle Scholar
Larsen, TKMcGlashan, THMoe, LCFirst-episode schizophrenia: I. Early course parameters Schizophr Bull 1996 ; 22 : 241-56CrossRefGoogle ScholarPubMed
Lecrubier, YSheehan, DVWeiller, EAmorin, PBonora, ISheehan, KH et al. The Mini International Neuropsychiatric Interview (MINI). A short diagnostic structured interview: reliability and validity according to the CID] Eur Psychiatry 1997; 12: 224-31CrossRefGoogle Scholar
Loebel, ADLieberman, JAAlvir, JMMayerhoff, DIGeisler, SHSzymanski, SRDuration of psychosis and outcome in firstepisode schizophrenia Am J Psychiatry 1992 ; 149 : 1183-8Google Scholar
McGlashan, THJohannessen, JOEarly detection and intervention with schizophrenia: rationale Schizophr Bull 1996 ; 22 : 201-22CrossRefGoogle ScholarPubMed
McKenzie, Kvan OS, JFahy, TJones, PHarvey, IToone, B et al. Psychosis with good prognosis in Afro-Caribbean people now living in the United Kingdom BMJ 1995 ; 311 : 1325-8CrossRefGoogle ScholarPubMed
Maurer, KHäfner, HMethodological aspects of onset assessment in schizophrenia Schirophr Res 1995 ; 15 : 265-76CrossRefGoogle Scholar
Norusis, MJSPSS for Windows 5.0.1 Chicago: SPPS lnc; 1992Google Scholar
Ram, RBromet, EJEaton, WWPato, CSchwartz, JEThe natural course of schizophrenia: a review of first-admission studies Schizophr Bull 1992 ; 18 : 185–207CrossRefGoogle ScholarPubMed
Vaglum, PEarlier detection and intervention in schizophrenia: unsolved questions Schizophr Bull 22 ; 1996 : 347-51CrossRefGoogle ScholarPubMed
van OS, JFahy, TAJones, PHarvey, ISham, PLewis, S et al. Psychopathological syndromes in the functional psychoses. Associations with course and outcome Psychol Med 1995 ; 26 : 161-76CrossRefGoogle Scholar
van OS, JTakei, NVerdoux, HDelespaul, PEarly detection of schizophrenia Br J Psychiatry 1997 ; 170 : 579CrossRefGoogle ScholarPubMed
Verdoux, HVan OS, ISham, PCJones, PBGilvarry, KMurray, RMDoes familiality predispose to both emergence and persistence of psychosis? A follow-up study Br J Psychiatry 1996 ; 168 : 620-6CrossRefGoogle ScholarPubMed
Waddington, JLYoussef, HAKinsella, ASequential cross-sectional and 10-years prospective study of severe negative symptoms in relation to duration of initially untreated psychosis in chronic schizophrenia Psychol Med 25 ; 1995 : 849-57CrossRefGoogle Scholar
Wyatt, RJNeuroleptics and the natural course of schizophrenia Schizophr Bull 1991 ; 17 : 325-51CrossRefGoogle ScholarPubMed
Wyatt, RJGreen, MFTuma, AHLong-term morbidity associated with delayed treatment of first admission schizophrenic patients: a re-analysis of the Camarillo State Hospital data Psychol Med 1997 ; 27 : 26l-8CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.