Benign symmetric lipomatosis Launois-Bensaude: Report of ten cases and review of the literature
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Diagnostic Pathology: Pediatric Neoplasms
2018, Diagnostic Pathology: Pediatric NeoplasmsParapharyngeal space lipomatosis with secondary dyspnea, disphagia and disphonia
2015, International Journal of Surgery Case ReportsCitation Excerpt :In this case, the differential diagnosis in this case included two entities: Madelung–Launois disease (benign symmetric lipomatosis) [6], and lipoma. Benign symmetric lipomatosis is an entity of unknown etiology, Kodish [7] stated that it was the result of hypertrophy of brown adipose tissue; it was first described in 1846 by Benjamin Brodie [8], and subsequently by Otto Madelung in 1888 and a decade later Launois and Besaunde [8] presented two case studies of 35 and 30 patients respectively; it predominantly affected males with reports emerging that refer to a ratio of 15:1, with a range of age of onset between 20 and 60 years; a pattern for family history has not yet been discovered and it is considered to be a sporadically occurring entity; there are some reports of family history, with dominant autosomal patterns of inheritance [6]. Lipomas constitute a very rare tumor in the parapharengeal space, as previously only 11 cases had been reported in the literature, presenting features which may include symptoms of pressure, with signs such as obstructive dysphagia and airway obstruction, sleep apnea manifested as dyspnea,similar to the present case [3–5,9,10].
Distal acquired benign symmetric lipomatosis: A rare subtype of an uncommon entity
2013, Journal of the American Academy of DermatologyMadelung's disease associated with polyneuropathy and symptomatic hypokalemia
2013, Journal of the Formosan Medical AssociationCitation Excerpt :Besides, image of fatty accumulations shows that the fatty bulk in MSL is noncapsulated and distributed along vascular and muscular planes, in contrast with lipoma, which is capsulated in subcutaneous space. Most patients are associated with alcoholism, but the casual effect between alcohol and MSL is unknown.1,2,4,5 Alcoholism-related macrocytic anemia and elevated liver enzyme are noted.
Madelung's disease: A case report
2012, Italian Journal of MedicineMultiple symmetrical lipomatosis: Case report and literature review
2012, Journal of Laryngology and Otology