[69] Exacerbation of superoxide radical formation by Paraquat☆
References (21)
- et al.
Biochim. Biophys. Acta
(1973) - et al.
Toxicol. Appl. Pharmacol.
(1975) - et al.
J. Biol. Chem.
(1978) FEBS Lett.
(1975)- et al.
Arch. Biochem. Biophys.
(1977) - et al.
J. Biol. Chem.
(1977) - et al.
Arch. Biochem. Biophys.
(1979) - et al.
J. Biol. Chem.
(1956) - et al.
J. Biol. Chem.
(1979) - et al.
Cited by (54)
Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis
2019, Free Radical Biology and MedicineCitation Excerpt :To investigate the consequences of a primary increase in ROS specifically within the mitochondrial compartment, we used the mitochondria-targeted compound MitoParaquat (MitoPQ) [31]. MitoPQ was designed based upon the conjugation of a paraquat moiety (1,1’-dimethyl-4,4’-bipyridinium dichloride) [32] with the mitochondria targeting triphenylphosphonium group. At the flavin site of complex I in the electron transport chain, MitoPQ accepts an electron to generate a radical monocation that reacts rapidly with oxygen to specifically generate superoxide, which is the proximal ROS species produced endogenously [33].
Interaction of methyl viologen-induced chloroplast and mitochondrial signalling in Arabidopsis
2019, Free Radical Biology and MedicineCitation Excerpt :Paraquat is the common name of the herbicide methyl viologen (MV; N,-N′-dimethyl-4,-4′-bipyridinium dichloride), which acts in the production of ROS via a light dependent mechanism. In chloroplasts MV competes with ferredoxin for electrons on the acceptor side of photosystem I (PSI) [3,4] and forms the MV cation radical, which reacts instantly with O2 to form superoxide (O2. -) [5]. O2. -
Sexual dimorphism in oxidant-induced adaptive homeostasis in multiple wild-type D. melanogaster strains
2017, Archives of Biochemistry and BiophysicsSelective superoxide generation within mitochondria by the targeted redox cycler MitoParaquat
2015, Free Radical Biology and MedicineOxidative stress elicited by insecticides: A role for the adipokinetic hormone
2011, General and Comparative EndocrinologyCitation Excerpt :Recently it has been proven that AKHs [29,50], ecdysteroids [34], juvenile hormone [25] and glucagon [1] play this role in insects. Application of the oxidative stressors such as paraquat [21], Gallanthus nivalis agglutinin and Bacillus thuringiensis toxin [29], and insecticides endosulfan and malathion (this study) elevates the titre of AKHs in haemolymph and depending on duration of the stressor incidence, also in the CNS. All those findings suggest that AKH might be involved in the activation of an antioxidant protection processes.
- ☆
Paper Number 8792 of the Journal Series of the North Carolina Agricultural Research Service, Raleigh, NC 27650. The use of trade names in this publication does not imply endorsement by the North Carolina Agricultural Research Service of the products named, nor criticism of similar ones not mentioned.